1,2,3,4-Tetrafluorobenzene
1,2,3,4-Tetrafluorobenzene (CAS: 551-62-2, C6H2F4) is a fluorinated aromatic compound with a molecular weight of 150.07 g/mol. This clear, colourless liquid is recognised for its utility as a building block in organic synthesis. Its specific substitution pattern of fluorine atoms on the benzene ring makes it a valuable intermediate in the development of advanced materials and complex organic molecules, particularly within the pharmaceutical and agrochemical sectors.
- Synonyms
- 4-Tetrafluorobenzene551-62-2C6H2F4
Organic Synthesis Intermediate
1,2,3,4-Tetrafluorobenzene serves as a key building block in the synthesis of complex organic molecules. Its unique fluorination pattern allows for regioselective reactions, enabling the construction of novel chemical entities for research and development.
Pharmaceutical Research
This compound is employed in medicinal chemistry to introduce fluorinated phenyl moieties into drug candidates. Fluorine substitution can favourably alter pharmacokinetic properties such as metabolic stability and lipophilicity.
Agrochemical Development
In the agrochemical industry, 1,2,3,4-Tetrafluorobenzene is utilised as an intermediate for the creation of new pesticides and herbicides. The incorporation of fluorine can enhance biological activity and environmental persistence profiles.
Materials Science
The electron-withdrawing nature of fluorine atoms makes this compound useful in the synthesis of specialty polymers and advanced materials with specific electronic or optical properties.
| Molecular weight | 150.07 |
|---|---|
| Empirical formula | C6H2F4 |
| Assay | 99% |
| Boiling point | 95 °C(lit.) |
| Density | 1.4 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.408(lit.) |
| Melting point | −42 °C(lit.) |
Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 20 °C / 68 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2,3,4-Tetrafluorobenzene used for?
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1,2,3,4-Tetrafluorobenzene is primarily used as a versatile building block in organic synthesis, particularly for introducing fluorinated aromatic structures into pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and formula for 1,2,3,4-Tetrafluorobenzene?
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The CAS number for 1,2,3,4-Tetrafluorobenzene is 551-62-2, and its molecular formula is C6H2F4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2,3,4-Tetrafluorobenzene with a minimum assay of 99%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated otherwise.
What are the main safety concerns when handling 1,2,3,4-Tetrafluorobenzene?
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1,2,3,4-Tetrafluorobenzene is a highly flammable liquid and vapour (H225) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always handle with appropriate personal protective equipment, including eye protection, gloves, and in a well-ventilated area or with respiratory protection.
How is 1,2,3,4-Tetrafluorobenzene packed, shipped, and exported?
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As a specialist global supplier, Tech Serve Solutions packs and ships 1,2,3,4-Tetrafluorobenzene in compliance with all relevant international transportation regulations for hazardous materials, including UN 1993 BF 3 / PG II classification.
How can I request a quote or sample for 1,2,3,4-Tetrafluorobenzene?
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To request a quote or a sample of 1,2,3,4-Tetrafluorobenzene, please contact our sales department via the website or by phone with your specific requirements.
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