2-Chloro-4-(trifluoromethyl)phenyl isocyanate
2-Chloro-4-(trifluoromethyl)phenyl isocyanate (CAS: 51488-22-3), with the molecular formula ClC6H3(CF3)NCO and a molecular weight of 221.56 g/mol, is a reactive organic compound. It serves as a valuable building block in organic synthesis. This isocyanate is typically utilised in the creation of more complex molecules, particularly in the pharmaceutical and agrochemical industries, owing to its specific functional groups.
Organic Synthesis Intermediate
This isocyanate is a key intermediate in the synthesis of diverse organic compounds. Its reactive isocyanate group readily participates in addition reactions, making it useful for constructing complex molecular architectures.
Pharmaceutical & Agrochemical Research
It finds application in the research and development of new pharmaceutical agents and agrochemicals. The trifluoromethyl and chloro substituents offer unique electronic and steric properties for molecular design.
Specialty Chemical Production
Utilised in the production of various specialty chemicals, leveraging its specific reactivity for targeted chemical transformations in multi-step synthesis processes.
| Molecular weight | 221.56 |
|---|---|
| Linear formula | ClC6H3(CF3)NCO |
| Assay | 98% |
| Boiling point | 199 °C(lit.) |
| Density | 1.441 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.493(lit.) |
Hazard statements
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 99 °C / 210.2 °F |
| Transport (UN / ADR) | UN 2206 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38-42 |
| Safety statements (S) | 23-26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4-(trifluoromethyl)phenyl isocyanate used for?
+
2-Chloro-4-(trifluoromethyl)phenyl isocyanate (CAS: 51488-22-3) is primarily used as a building block and intermediate in organic synthesis, particularly for the development of pharmaceutical and agrochemical compounds.
What are the CAS number and molecular formula?
+
The CAS number is 51488-22-3 and the molecular formula is ClC6H3(CF3)NCO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Chloro-4-(trifluoromethyl)phenyl isocyanate with an assay of 98%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Chloro-4-(trifluoromethyl)phenyl isocyanate be handled?
+
This compound is classified as Danger with hazards including skin and respiratory irritation, and potential for allergic reaction (H312, H315, H319, H332, H334, H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection. Ensure adequate ventilation.
How is this chemical packed and shipped?
+
2-Chloro-4-(trifluoromethyl)phenyl isocyanate is packed and shipped in accordance with UN 2206 regulations (Class 6.1, PG 3). TSS is a global supplier and exporter, adhering to all relevant shipping and handling requirements.
How can I request a quote or sample?
+
To request a quote or sample of 2-Chloro-4-(trifluoromethyl)phenyl isocyanate, please contact our sales team through the website or designated inquiry channels.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis