2-Chloro-4-(trifluoromethyl)pyridine
2-Chloro-4-(trifluoromethyl)pyridine (CAS 81565-18-6), with chemical formula C6H3ClF3N and a molecular weight of 181.54 g/mol, is a halogenated pyridine derivative. This compound serves as a valuable intermediate and building block in organic synthesis. It is primarily utilised in the development of novel pharmaceuticals and agrochemicals due to the presence of both a reactive chlorine atom and a trifluoromethyl group on the pyridine ring, enabling diverse chemical transformations.
Pharmaceutical Intermediate
Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Its unique structure allows for the introduction of the trifluoromethylpyridine moiety into complex drug molecules.
Agrochemical Synthesis
Used in the development of new pesticides, herbicides, and fungicides. The trifluoromethyl group often imparts desirable biological activity and metabolic stability in agrochemical compounds.
Organic Synthesis Reagent
A versatile reagent in academic and industrial research laboratories for creating complex heterocyclic compounds. It facilitates various coupling and substitution reactions.
Material Science
Potential applications in the synthesis of novel materials, where the fluorinated pyridine core can influence electronic or physical properties.
| Molecular weight | 181.54 |
|---|---|
| Empirical formula | C6H3ClF3N |
| Assay | 97% |
| Boiling point | 146-147 °C(lit.) |
| Density | 1.411 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4490(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4-(trifluoromethyl)pyridine used for?
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2-Chloro-4-(trifluoromethyl)pyridine is primarily used as a building block and intermediate in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals.
What is the CAS number and chemical formula for 2-Chloro-4-(trifluoromethyl)pyridine?
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The CAS number is 81565-18-6 and the chemical formula is C6H3ClF3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-4-(trifluoromethyl)pyridine with a minimum purity of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Chloro-4-(trifluoromethyl)pyridine be handled?
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Handle with appropriate personal protective equipment, including eyeshields, face shields, and gloves. Ensure adequate ventilation or use a respirator. It is classified as an irritant to skin, eyes, and respiratory tract (H315-H319-H335).
How is 2-Chloro-4-(trifluoromethyl)pyridine packed and shipped?
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This chemical is packed in compliance with transport regulations, including UN 1993 C3/PGIII, and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for 2-Chloro-4-(trifluoromethyl)pyridine?
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Please contact our sales team via our website or direct inquiry to request a sample or a formal quotation.
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