2-Chloro-4-(trifluoromethyl)pyridine-3-carboxylic acid
2-Chloro-4-(trifluoromethyl)pyridine-3-carboxylic acid (CAS 590371-81-6) is a halogenated heterocyclic compound with the molecular formula C7H3ClF3NO2 and a molecular weight of 225.55 g/mol. This pyridine derivative serves as a valuable building block in organic synthesis. Its structure, featuring a trifluoromethyl group and a carboxylic acid moiety on a chlorinated pyridine ring, makes it a useful intermediate for the development of complex molecules, particularly in agrochemical and pharmaceutical research. Available at 97% purity.
- IUPAC
- 2-Chloro-4-(trifluoromethyl)nicotinic acid
- Synonyms
- 2-Chloro-4-(trifluoromethyl)nicotinic acid

Agrochemical Intermediate
This compound can be utilised in the synthesis of novel agrochemicals. The trifluoromethylpyridine scaffold is found in various herbicides and pesticides, suggesting its potential as a precursor in this field.
Pharmaceutical Building Block
As a functionalised pyridine, it is a key intermediate for constructing more complex pharmaceutical candidates. Its unique combination of substituents allows for diverse synthetic transformations.
Organic Synthesis Reagent
Utilised in research laboratories for constructing carbon-carbon and carbon-heteroatom bonds. It is a versatile reagent for introducing the trifluoromethylpyridine moiety into target molecules.
| Molecular weight | 225.55 |
|---|---|
| Empirical formula | C7H3ClF3NO2 |
| Assay | 97% |
| Melting point | 157-160 °C |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 21/22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4-(trifluoromethyl)pyridine-3-carboxylic acid used for?
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This compound is primarily used as a building block in organic synthesis, particularly in the development of agrochemicals and pharmaceuticals. It serves as a key intermediate for introducing the trifluoromethylpyridine structure into more complex molecules.
What is the CAS number and molecular formula?
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The CAS number is 590371-81-6 and the molecular formula is C7H3ClF3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-4-(trifluoromethyl)pyridine-3-carboxylic acid at a purity of 97%. This product is suitable for research and chemical synthesis purposes. Tech Serve Solutions does not represent this product as USP, BP, or EP grade.
How should 2-Chloro-4-(trifluoromethyl)pyridine-3-carboxylic acid be handled?
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This compound is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation. Refer to the safety data sheet for full handling instructions.
Is this chemical a controlled substance?
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Based on the provided data, there is no indication that 2-Chloro-4-(trifluoromethyl)pyridine-3-carboxylic acid is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, pharmaceutical intermediates, and laboratory reagents. Specific packing and shipping details are available upon request, adhering to all relevant international regulations.
How can I request a quote or sample?
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To request a quote or a sample of 2-Chloro-4-(trifluoromethyl)pyridine-3-carboxylic acid, please contact the Tech Serve Solutions sales department through our website or by phone.
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