2-Chloro-4-(trifluoromethoxy)aniline
2-Chloro-4-(trifluoromethoxy)aniline (CAS 69695-61-0) is a valuable organic compound with the molecular formula F3COC6H3(Cl)NH2 and a molecular weight of 211.57. This substituted aniline derivative serves as a key building block in complex chemical syntheses, particularly within the agrochemical and pharmaceutical sectors. Its trifluoromethoxy and chloro substituents offer unique reactivity, making it an important intermediate for introducing specific functional groups into target molecules.
Agrochemical Synthesis
This compound is utilised as an intermediate in the synthesis of novel agrochemicals. Its structural features allow for the development of compounds with specific biological activities relevant to crop protection.
Pharmaceutical Intermediates
It serves as a crucial building block in the preparation of active pharmaceutical ingredients (APIs). The trifluoromethoxy group, in particular, is often incorporated to enhance metabolic stability and lipophilicity of drug candidates.
Organic Synthesis Reagent
As a functionalised aniline, it is employed in various organic transformations, enabling the construction of more complex molecular architectures for research and development purposes.
| Molecular weight | 211.57 |
|---|---|
| Linear formula | F3COC6H3(Cl)NH2 |
| Assay | 97% |
| Boiling point | 94-96 °C/11 mmHg |
| Density | 1.524 g/mL at 25 °C |
| Refractive index | n20/D 1.428 |
Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 98 °C / 208.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36-43 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4-(trifluoromethoxy)aniline used for?
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2-Chloro-4-(trifluoromethoxy)aniline is primarily used as a chemical intermediate in the synthesis of agrochemicals and pharmaceuticals, as well as a building block in general organic synthesis.
What are the CAS number and molecular formula?
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The CAS number for 2-Chloro-4-(trifluoromethoxy)aniline is 69695-61-0, and its molecular formula is F3COC6H3(Cl)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-4-(trifluoromethoxy)aniline with an assay of 97%. This product is not represented as USP, BP, or EP grade.
What are the primary safety hazards associated with this chemical?
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This compound is classified as dangerous. It can be harmful if swallowed (H302), causes serious eye irritation (H319), and may cause allergy or asthma symptoms or breathing difficulties if inhaled (H334). Appropriate personal protective equipment, including eye protection, gloves, and respiratory protection, must be used.
How is 2-Chloro-4-(trifluoromethoxy)aniline packed and shipped?
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Tech Serve Solutions reliably packs and ships fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all necessary safety and transport regulations.
How can I request a sample or quote?
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To request a sample or a quote for 2-Chloro-4-(trifluoromethoxy)aniline, please contact our sales team via the website or through direct inquiry.
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