Methyl 4-methoxysalicylate
Methyl 4-methoxysalicylate (CAS 5446-02-6), with the chemical formula CH3OC6H3(OH)CO2CH3 and a molar mass of 182.17 g/mol, is an organic compound used as a building block in chemical synthesis. It functions as an ester and carbonyl compound, contributing to the creation of more complex molecules. This chemical is primarily utilised in laboratory settings for research and development purposes, particularly in organic synthesis pathways.
- IUPAC
- Methyl 2-hydroxy-4-methoxybenzoate
Organic Synthesis Intermediate
Methyl 4-methoxysalicylate serves as a valuable intermediate in the synthesis of complex organic molecules. Its structure, featuring both hydroxyl and ester functionalities, allows for diverse chemical transformations.
Natural Product Synthesis
This compound has been employed in the enantioselective synthesis of bioactive natural products, such as coriandrone A and B, highlighting its utility in advanced chemical research.
Building Block for Fine Chemicals
As a C8-C9 building block, it is instrumental in the construction of various fine chemicals and pharmaceutical intermediates, offering a defined structural motif for further elaboration.
| Molecular weight | 182.17 |
|---|---|
| Linear formula | CH3OC6H3(OH)CO2CH3 |
| Assay | 98% |
| Application | Methyl 4-methoxysalicylate (methyl 2-hydroxy-4-methoxybenzoate) was used in the enantioselective synthesis of (+)-coriandrone A and B, two bioactive natural products1. |
| Melting point | 50-53 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 4-methoxysalicylate used for?
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Methyl 4-methoxysalicylate is used as an intermediate in organic synthesis, a building block for fine chemicals, and in the synthesis of natural products. It is primarily utilised in laboratory research and development.
What is the CAS number and chemical formula for Methyl 4-methoxysalicylate?
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The CAS number is 5446-02-6 and the chemical formula is CH3OC6H3(OH)CO2CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 4-methoxysalicylate with a purity of 98%. This product is supplied for research and development use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Methyl 4-methoxysalicylate be handled safely?
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Handle Methyl 4-methoxysalicylate with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust, fumes, or vapours. It is classified as a warning substance with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation).
Is Methyl 4-methoxysalicylate a controlled substance?
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Based on the provided data, Methyl 4-methoxysalicylate is not indicated as a controlled substance.
How is Methyl 4-methoxysalicylate shipped and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Methyl 4-methoxysalicylate, adhering to all relevant shipping and export regulations.
How can I request a sample or quote for Methyl 4-methoxysalicylate?
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To request a sample or a quote for Methyl 4-methoxysalicylate, please contact the Tech Serve Solutions sales team through our website or via direct inquiry.
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