Methyl 4-methoxy-2-indolecarboxylate
Methyl 4-methoxy-2-indolecarboxylate (CAS: 111258-23-2, C11H11NO3) is a high-purity chemical compound with a molecular weight of 205.21 g/mol. As a versatile indole derivative, it serves as a key building block in complex organic synthesis. Its applications span various chemical reactions, including annulations, Heck reactions, and the preparation of specific inhibitors and indole-based derivatives, making it valuable for research and development in medicinal chemistry and materials science.
Reactant in [3+2] Annulation Reactions
Methyl 4-methoxy-2-indolecarboxylate functions as a crucial reactant in [3+2] annulation reactions, enabling the formation of novel heterocyclic systems. This application is significant in synthetic organic chemistry for constructing complex molecular architectures.
Preparation of Inhibitors
This compound is employed as a reactant in the preparation of inhibitors for mammalian secreted phospholipases A2. Its structural features are integral to designing molecules with specific biological activities.
Reactant in Heck Reactions
Utilised in Heck reactions, Methyl 4-methoxy-2-indolecarboxylate facilitates carbon-carbon bond formation, a fundamental transformation in organic synthesis. This reaction is widely applied in the development of pharmaceuticals and fine chemicals.
Synthesis of Indole Fatty Alcohol Derivatives
The compound serves as a reactant in the synthesis of indole fatty alcohol derivatives. These derivatives can be of interest for their potential applications in various chemical and biological fields.
Methylation Reactions
Methyl 4-methoxy-2-indolecarboxylate can participate in methylation reactions, contributing to the modification and functionalisation of organic molecules. This is a common strategy in developing new chemical entities.
| Molecular weight | 205.21 |
|---|---|
| Empirical formula | C11H11NO3 |
| Assay | 99% |
| Application | • reactant in [3+2] annulation reactions1• reactant in preparation of inhibitors of mammalian secreted phospholipases A22• reactant in Heck reactions3• reactant in preparation of indole fatty alcohol derivatives4• reactant in methylation reactions5 |
| Melting point | 140-142 °C(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 4-methoxy-2-indolecarboxylate used for?
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Methyl 4-methoxy-2-indolecarboxylate is used as a reactant in various chemical syntheses, including [3+2] annulation reactions, Heck reactions, and in the preparation of inhibitors of mammalian secreted phospholipases A2 and indole fatty alcohol derivatives.
What is the CAS number and formula for Methyl 4-methoxy-2-indolecarboxylate?
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The CAS number for Methyl 4-methoxy-2-indolecarboxylate is 111258-23-2, and its empirical formula is C11H11NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 4-methoxy-2-indolecarboxylate with a minimum assay of 99%. TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the safety and handling recommendations for Methyl 4-methoxy-2-indolecarboxylate?
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Based on its classification (WGK Germany 3), Methyl 4-methoxy-2-indolecarboxylate is considered hazardous to water and should be handled with appropriate protective measures to avoid contact with skin, eyes, and inhalation. Consult the Safety Data Sheet (SDS) for detailed information.
How is Methyl 4-methoxy-2-indolecarboxylate packed, shipped, and exported?
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Tech Serve Solutions expertly packs, ships, and exports chemicals globally, ensuring compliance with all international regulations for hazardous materials. Specific packaging details are available upon request.
How can I request a sample or quote for Methyl 4-methoxy-2-indolecarboxylate?
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To request a sample or quote, please use the contact form on our website or contact our sales department directly. Our team will respond promptly to your inquiry.
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