1,4,7,10-Tetraazacyclododecane tetrahydrochloride
1,4,7,10-Tetraazacyclododecane tetrahydrochloride (CAS: 1045-25-7), with the molecular formula C8H20N4 · 4HCl and a molecular weight of 318.11 g/mol, is a significant macrocyclic amine salt. It is primarily utilised as a chelating agent and in chemical synthesis. Its structure makes it adept at forming stable complexes with various metal ions, underpinning its utility in research and development settings.
- Synonyms
- 10-Tetraazacyclododecane tetrahydrochloride1045-25-7C8H20N4 · 4HCl

Metal Ion Chelation
This compound acts as a powerful chelating agent, forming stable complexes with a range of metal ions. Its macrocyclic structure is particularly effective in sequestering specific cations, finding use in analytical chemistry and separation processes.
Chemical Synthesis Intermediate
As a versatile building block in organic synthesis, 1,4,7,10-Tetraazacyclododecane tetrahydrochloride is employed in the preparation of more complex molecules. Its amine functionalities allow for further derivatization and incorporation into novel chemical structures.
Complexation Studies
Researchers utilise this tetraazamacrocycle to study coordination chemistry and the behaviour of metal complexes. It serves as a ligand in the development of new catalytic systems and materials with specific electronic or magnetic properties.
| Molecular weight | 318.11 |
|---|---|
| Empirical formula | C8H20N4 · 4HCl |
| Assay | ≥97.0% (N) |
| Melting point | 297-300 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,4,7,10-Tetraazacyclododecane tetrahydrochloride primarily used for?
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1,4,7,10-Tetraazacyclododecane tetrahydrochloride (CAS: 1045-25-7) is mainly utilised as a chelating agent and an intermediate in chemical synthesis, particularly for forming stable complexes with metal ions.
What are the CAS number and molecular formula for 1,4,7,10-Tetraazacyclododecane tetrahydrochloride?
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The CAS number is 1045-25-7 and the molecular formula is C8H20N4 · 4HCl.
What grade and purity does Tech Serve Solutions supply for 1,4,7,10-Tetraazacyclododecane tetrahydrochloride?
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Tech Serve Solutions supplies 1,4,7,10-Tetraazacyclododecane tetrahydrochloride with an assay of ≥97.0% (N). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.
What are the primary safety hazards associated with 1,4,7,10-Tetraazacyclododecane tetrahydrochloride?
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This compound is classified with GHS07 and a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment should be used during handling.
How is 1,4,7,10-Tetraazacyclododecane tetrahydrochloride typically packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packaging details are available upon request, and all shipments comply with international shipping regulations for chemical substances.
How can I request a sample or a quote for 1,4,7,10-Tetraazacyclododecane tetrahydrochloride?
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To request a sample or a quote, please contact our sales team directly through our website or by calling our customer service number. Please reference the product name and CAS number (1045-25-7).
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