2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt hydrate
2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt hydrate (CAS: 76204-02-9) is a fluorescent enzyme substrate. This hydrate is primarily employed in biochemical research for the detection and quantification of neuraminidase activity. Its ability to emit fluorescence upon enzymatic cleavage makes it a valuable tool in various biological assays and diagnostic applications, facilitating sensitive and specific measurements.
- IUPAC
- 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid sodium salt hydrate
- Synonyms
- 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid sodium salt hydrate
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Neuraminidase Activity Assays
Utilised as a specific substrate to measure the activity of neuraminidase enzymes. Enzymatic cleavage releases the fluorescent 4-methylumbelliferone, allowing for sensitive detection.
Fluorescence Spectroscopy
Its fluorescent properties make it suitable for quantitative analysis using fluorescence spectroscopy, with distinct excitation and emission wavelengths before and after enzymatic hydrolysis.
Biochemical Research
Serves as a valuable reagent in studies investigating carbohydrate metabolism, glycosidase function, and related biochemical pathways.
Diagnostic Applications
Can be applied in developing diagnostic tests for conditions where neuraminidase activity is a relevant biomarker, offering a sensitive detection method.
| Empirical formula | C21H24NNaO11 · xH2O |
|---|---|
| Assay | ≥96.5% (HPLC) |
| Solubility | H2O: soluble50 mg/mL, clear, very slightly yellow |
| Storage temperature | −20°C |
| Impurities tested | ≤0.5% free 4-methylumbelliferone≤10% water |
| Suitability | suitable for fluorescence |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioReagent |
|---|---|
| Fluorescence | λex 315 nm; λem 374 nm (pH.7.0)λex 365 nm; λem 445 nm (after cleavage by neuraminidase) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt hydrate used for?
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This compound is primarily used as a fluorescent enzyme substrate for the detection and quantification of neuraminidase activity in biochemical research and diagnostic applications.
What is the CAS number and formula for this product?
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The CAS number for the anhydrous form is 76204-02-9. The empirical formula is C21H24NNaO11 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥96.5% (HPLC). It is suitable for fluorescence applications. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should this chemical be handled safely?
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When handling, wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the safety data sheet for full handling information. This compound has a WGK Germany rating of 3.
Is this product available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a quote or sample?
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Please contact our sales team through our website or by phone to request a quote or a sample of 2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt hydrate.
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