(6-Chlorobenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate
(6-Chlorobenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (CAS: 893413-42-8; Formula: C18H27ClF6N6OP2; MW: 554.84) is a high-purity phosphonium salt. It serves as a valuable reagent in organic synthesis, particularly for coupling reactions. TSS supplies this compound with an assay of 97%, typically stored under refrigeration at 2-8°C for optimal stability and performance in demanding synthetic applications.
- IUPAC
- TPTDP
Peptide Synthesis
This phosphonium salt is widely employed as a coupling reagent in solid-phase and solution-phase peptide synthesis. It efficiently facilitates the formation of amide bonds between amino acids, enabling the construction of complex peptide chains.
Organic Synthesis
Beyond peptide synthesis, it finds application in general organic synthesis for the formation of ester and amide linkages. Its reliable reactivity makes it a useful tool for chemists in various synthetic transformations.
Reagent for Amidation
The compound is an effective reagent for the amidation of carboxylic acids. It activates the carboxyl group, promoting facile reaction with primary and secondary amines to yield the corresponding amides.
| Molecular weight | 554.84 |
|---|---|
| Empirical formula | C18H27ClF6N6OP2 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 174-180 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (6-Chlorobenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate used for?
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This compound is primarily used as a coupling reagent in organic synthesis, notably for peptide and amide bond formation. It is also utilized for the amidation of carboxylic acids.
What is the CAS number and formula for this product?
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The CAS number is 893413-42-8 and the molecular formula is C18H27ClF6N6OP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (6-Chlorobenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate with an assay of 97%. This is a technical/research grade material and is not represented as USP, BP, or EP.
How should this chemical be handled and stored?
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This chemical is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Store at 2-8°C.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals. Please contact us for export details and shipping options.
How can I request a sample or quote?
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To request a sample or a quote for (6-Chlorobenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate, please use the contact form on our website or call our sales department directly.
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