Diethyl (N-methoxy-N-methylcarbamoylmethyl)phosphonate
Diethyl (N-methoxy-N-methylcarbamoylmethyl)phosphonate, identified by CAS number 124931-12-0, is a chemical compound with the molecular formula CH₃ON(CH₃)COCH₂P(O)(OC₂H₅)₂ and a molecular weight of 239.21 g/mol. It functions as a Wittig carbonylating reagent. This compound is valuable in chemical synthesis for C-C bond formation and olefination reactions, serving as a key component in the Horner-Wadsworth-Emmons reaction pathway.
- IUPAC
- N-Methoxy-N-methyl-phosphonoacetamide diethyl ester,N-Methoxy-N-methyl-2-(diethyl phosphono)acetamide,Diethyl N-methoxy-N-methylphosphonoacetamide,Diethylphosphonoacetic acid N-methyl-N-methoxyamide
- Synonyms
- N-Methoxy-N-methyl-phosphonoacetamide diethyl esterN-Methoxy-N-methyl-2-(diethyl phosphono)acetamideDiethyl N-methoxy-N-methylphosphonoacetamideDiethylphosphonoacetic acid N-methyl-N-methoxyamide
Wittig Carbonylating Reagent
This compound serves as a Wittig carbonylating reagent, enabling the introduction of carbonyl groups in organic synthesis. It is particularly useful for constructing carbon-carbon double bonds through olefination reactions.
Horner-Wadsworth-Emmons (HWE) Reagent
As a phosphonate ester, it is a type of reagent used in the Horner-Wadsworth-Emmons reaction. This reaction is a modification of the Wittig reaction and is widely employed for the synthesis of alkenes.
C-C Bond Formation
The reagent facilitates the formation of new carbon-carbon bonds, a fundamental process in the construction of complex organic molecules. Its application is crucial in multi-step syntheses.
General Chemical Synthesis
This compound is a versatile synthetic reagent applicable to various organic transformations. Its specific reactivity profile makes it a useful tool for chemists in research and development.
| Molecular weight | 239.21 |
|---|---|
| Linear formula | CH3ON(CH3)COCH2P(O)(OC2H5)2 |
| Assay | 96% |
| Boiling point | 90 °C/17 mmHg(lit.) |
| Density | 1.163 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.455(lit.) |
| Application | Wittig carbonylating reagent.7 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl (N-methoxy-N-methylcarbamoylmethyl)phosphonate used for?
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Diethyl (N-methoxy-N-methylcarbamoylmethyl)phosphonate is primarily used as a Wittig carbonylating reagent and a Horner-Wadsworth-Emmons reagent for carbon-carbon bond formation and olefination reactions in chemical synthesis.
What are the CAS number and formula for this product?
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The CAS number is 124931-12-0, and the linear formula is CH₃ON(CH₃)COCH₂P(O)(OC₂H₅)₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 96%. We do not represent this product as USP, BP, EP, or pharmaceutical grade.
How should Diethyl (N-methoxy-N-methylcarbamoylmethyl)phosphonate be handled?
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This compound is a Warning substance and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, should be used. Avoid breathing vapour or mist and ensure adequate ventilation.
Is Diethyl (N-methoxy-N-methylcarbamoylmethyl)phosphonate a controlled substance?
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Based on the provided data, there is no indication that this compound is a scheduled or controlled substance.
How is this chemical packed and exported?
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As a global supplier, Tech Serve Solutions exports this chemical, adhering to all necessary regulations for safe transport and handling of chemical reagents.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team through the website or by phone, providing the product name and CAS number (124931-12-0).
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