Diethyl (difluoromethyl)phosphonate
Diethyl (difluoromethyl)phosphonate (CAS: 1478-53-1), with the chemical formula F2CHP(O)(OC2H5)2 and a molecular weight of 188.11 g/mol, is a fluorinated organic building block. This compound serves as a valuable intermediate in organic synthesis, particularly for introducing the difluoromethyl group into various molecular structures. Its properties make it suitable for research and development in pharmaceuticals, agrochemicals, and materials science, offering unique chemical functionalities for innovative applications.
Organic Synthesis Intermediate
Diethyl (difluoromethyl)phosphonate is primarily utilised as a versatile building block in organic chemistry. It enables the incorporation of the difluoromethyl moiety, a group known to modulate physicochemical and biological properties, into target molecules.
Fluorinated Compound Development
This phosphonate ester is instrumental in the synthesis of novel fluorinated compounds. Its application is relevant in the development of pharmaceuticals, agrochemicals, and advanced materials where fluorine incorporation can enhance efficacy, stability, or performance.
Research and Development
Researchers leverage Diethyl (difluoromethyl)phosphonate in exploratory synthesis and methodology development. It provides a reliable source of the difluoromethyl group for creating new chemical entities and exploring their potential applications.
| Molecular weight | 188.11 |
|---|---|
| Linear formula | F2CHP(O)(OC2H5)2 |
| Assay | 97% |
| Boiling point | 55 °C/0.5 mmHg(lit.) |
| Density | 1.199 g/mL at 25 °C(lit.)1.206 g/mL at 25 °C |
| Refractive index | n20/D 1.388(lit.)n20/D 1.388 |
| Storage temperature | 2-8°C |
| Flash point | 110 °C / 230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl (difluoromethyl)phosphonate used for?
+
Diethyl (difluoromethyl)phosphonate is used as a building block in organic synthesis, particularly for introducing the difluoromethyl group into molecules for pharmaceutical, agrochemical, and materials science research and development.
What are the CAS number and formula for Diethyl (difluoromethyl)phosphonate?
+
The CAS number is 1478-53-1, and its chemical formula is F2CHP(O)(OC2H5)2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Diethyl (difluoromethyl)phosphonate with an assay of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should Diethyl (difluoromethyl)phosphonate be handled and stored?
+
Diethyl (difluoromethyl)phosphonate has a flash point of 110°C (230°F) and should be handled with appropriate personal protective equipment in a well-ventilated area. It is recommended to store this compound at 2-8°C.
Is Diethyl (difluoromethyl)phosphonate a controlled substance?
+
Based on the provided data, Diethyl (difluoromethyl)phosphonate is not listed as a controlled substance.
How can I request a quote or sample?
+
To request a quote or sample of Diethyl (difluoromethyl)phosphonate, please contact our sales team through the website or by phone.
How is Diethyl (difluoromethyl)phosphonate packaged and exported?
+
Diethyl (difluoromethyl)phosphonate is carefully packaged to ensure stability and safety during transit. Tech Serve Solutions, as a global supplier, can export this chemical to various international destinations, adhering to all relevant shipping regulations.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis