4-Fluoro-3-methylbenzoyl chloride
Tech Serve Solutions presents 4-Fluoro-3-methylbenzoyl chloride (CAS 455-84-5), a fluorinated aryl building block with the molecular formula C8H6ClFO and a molecular weight of 172.58 g/mol. This acid halide serves as a key intermediate in organic synthesis, particularly for introducing the 4-fluoro-3-methylbenzoyl moiety into target molecules. Its reactivity makes it valuable in the development of novel compounds within the pharmaceutical and agrochemical sectors.
Pharmaceutical Intermediate
This compound is utilised in the synthesis of active pharmaceutical ingredients (APIs). Its structural features are incorporated into drug candidates, contributing to their pharmacological properties.
Agrochemical Synthesis
It serves as a building block for developing new agrochemicals, such as pesticides and herbicides. The fluorinated aromatic ring can impart desirable stability and efficacy to these products.
Material Science Research
The unique electronic and structural properties of fluorinated aromatic compounds make them useful in the research and development of advanced materials. This acid chloride can be a precursor for specialised polymers or functional materials.
Organic Synthesis Reagent
As an acid halide, it readily participates in acylation reactions, forming esters, amides, and other carbonyl derivatives. This makes it a versatile reagent for constructing complex organic molecules.
| Molecular weight | 172.58 |
|---|---|
| Linear formula | FC6H3(CH3)COCl |
| Assay | 97% |
| Boiling point | 129-133 °C/17 mmHg(lit.) |
| Density | 1.215 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5320(lit.) |
| Storage temperature | 2-8°C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 98 °C / 208.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluoro-3-methylbenzoyl chloride primarily used for?
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4-Fluoro-3-methylbenzoyl chloride is primarily used as an intermediate in organic synthesis, particularly for the introduction of the 4-fluoro-3-methylbenzoyl group in the preparation of pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and molecular formula for 4-Fluoro-3-methylbenzoyl chloride?
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The CAS number is 455-84-5 and the molecular formula is C8H6ClFO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fluoro-3-methylbenzoyl chloride with an assay of 97%. This product is a research-grade chemical and is not represented as USP, BP, or EP grade.
How should 4-Fluoro-3-methylbenzoyl chloride be handled safely?
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4-Fluoro-3-methylbenzoyl chloride is classified as Danger (GHS05) with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including face shields, gloves, and respirators (type ABEK), must be used. Handle in a well-ventilated area and follow all recommended safety precautions.
How is 4-Fluoro-3-methylbenzoyl chloride packed and shipped?
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This chemical is packed and shipped in accordance with international regulations for hazardous materials, specifically UN 3265, Hazard Class 8, Packing Group II.
How can I request a sample or quote for 4-Fluoro-3-methylbenzoyl chloride?
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To request a sample or a quote, please contact our sales team through the website or by calling our dedicated line. Provide your contact details and the required quantity.
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