2-[[4′-(Trifluoromethoxy)phenoxy]methyl]phenylboronic acid
2-\[[4′-(Trifluoromethoxy)phenoxy]methyl]phenylboronic acid (CAS: 849062-07-3) is an organoboron compound with the molecular formula C14H12BF3O4 and a molecular weight of 312.05 g/mol. It belongs to the class of aryl boronic acids, commonly employed as versatile building blocks in organic synthesis. Its structure, featuring a trifluoromethoxy-substituted phenoxy moiety, makes it a valuable reagent for cross-coupling reactions, particularly Suzuki-Miyaura couplings, for the construction of complex organic molecules.
![2-[[4′-(Trifluoromethoxy)phenoxy]methyl]phenylboronic acid (C14H12BF3O4) — chemical structure, CAS 849062-07-3; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F849062-07-3.png&w=3840&q=75)
Organic Synthesis Reagent
This compound serves as a key intermediate in the synthesis of complex organic molecules. Its aryl boronic acid functionality is particularly useful in palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling.
Pharmaceutical Intermediate
It can be employed in the development of novel pharmaceutical agents. The incorporation of the trifluoromethoxy group can influence the pharmacokinetic properties of drug candidates.
Materials Science
The unique structural features may lend themselves to applications in materials science, such as in the synthesis of functional polymers or organic electronic materials.
| Molecular weight | 312.05 |
|---|---|
| Empirical formula | C14H12BF3O4 |
| Melting point | 153-167 °C(lit.) |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-\[[4′-(Trifluoromethoxy)phenoxy]methyl]phenylboronic acid used for?
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This compound is primarily used as a building block in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions like the Suzuki-Miyaura coupling, and may serve as an intermediate in the development of pharmaceuticals and advanced materials.
What are the CAS number and formula for this product?
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The CAS number is 849062-07-3 and the empirical formula is C14H12BF3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific assay and purity are detailed in the product's technical specifications. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the specifications.
What are the safety and handling considerations for this product?
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This compound is classified with H413 hazard statement, indicating it may cause long lasting harmful effects to aquatic life. Appropriate personal protective equipment, including eyeshields, gloves, and a P1/N95 respirator filter, should be used. Handle in a well-ventilated area and avoid release into the environment.
Is this chemical exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or quote for 2-\[[4′-(Trifluoromethoxy)phenoxy]methyl]phenylboronic acid?
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Please contact our sales department via the website or email to request a sample or a quotation. Please include the product name and CAS number in your request.
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