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1,1,1,3,3,3-Hexafluoro-2-propanol

CAS 920-66-1(CF3)2CHOHChemical Synthesis

1,1,1,3,3,3-Hexafluoro-2-propanol (CAS: 920-66-1), with the molecular formula (CF₃)₂CHOH and a molecular weight of 168.04 g/mol, is a unique fluorinated alcohol. It serves as a versatile solvent and a critical building block in organic synthesis. Its distinct properties make it valuable in specialised chemical research and the development of advanced materials.

IUPAC
HFP,Hexafluoroisopropanol
Synonyms
3,3,3-Hexafluoro-2-propanol(CF3)2CHOHHFPHexafluoroisopropanol
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1,1,1,3,3,3-Hexafluoro-2-propanol ((CF3)2CHOH) — chemical structure, CAS 920-66-1; Chemistry, fine chemical supplied by Tech Serve Solutions
Chemical ReagentsAlcoholsBuilding BlocksC2 to C6Chemical SynthesisOrganic Building BlocksOxygen Compounds More...
01 /Applications

Polymer Synthesis

1,1,1,3,3,3-Hexafluoro-2-propanol is employed in the preparation of hexafluoroalcohol-functionalized methacrylate polymers. These polymers are utilised in lithographic and nanopatterning materials.

Specialty Solvent

Its unique polarity and hydrogen-bonding capabilities make it a useful solvent for dissolving challenging substrates and in specific reaction media.

Organic Synthesis Intermediate

As a fluorinated alcohol, it acts as a key building block in the synthesis of complex organic molecules and pharmaceutical intermediates.

02 /Properties
Molecular weight168.04
Linear formula(CF3)2CHOH
Assay≥99.5%
Boiling point59 °C(lit.)
Density1.596 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.275(lit.)
Application1,1,1,3,3,3-Hexafluoro-2-propanol was used for preparing hexafluoroalcohol-functionalized methacrylate polymers for lithographic/nanopatterning materials1.
Melting point−4 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H302Harmful if swallowed
  • H314Causes severe skin burns and eye damage
  • H332Harmful if inhaled

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US)
Transport (UN / ADR)UN 2922 8/PG 2
Water hazard class (WGK, DE)2
Hazard codes (EU)C
Risk statements (R)20/22-34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
920-66-1
MDL number
MFCD00011651
PubChem substance
24846695
Beilstein registry
1841007
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1,1,1,3,3,3-Hexafluoro-2-propanol used for?

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1,1,1,3,3,3-Hexafluoro-2-propanol is used as a specialty solvent and a building block in organic synthesis, particularly for preparing functionalized polymers used in lithography and nanopatterning.

What are the CAS number and chemical formula for 1,1,1,3,3,3-Hexafluoro-2-propanol?

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The CAS number is 920-66-1, and the chemical formula is (CF₃)₂CHOH.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 1,1,1,3,3,3-Hexafluoro-2-propanol with an assay of ≥99.5%. We do not represent this product as USP, BP, or EP grade.

How should 1,1,1,3,3,3-Hexafluoro-2-propanol be handled safely?

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This compound is classified as corrosive and harmful if swallowed or inhaled. Handling requires appropriate personal protective equipment, including gloves, goggles, and respiratory protection, and should be done in a well-ventilated area. Refer to the safety data sheet for full details.

Does Tech Serve Solutions export 1,1,1,3,3,3-Hexafluoro-2-propanol?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 1,1,1,3,3,3-Hexafluoro-2-propanol.

How can I request a quote or sample for 1,1,1,3,3,3-Hexafluoro-2-propanol?

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Please contact our sales team via the website or phone to request a quote or sample for 1,1,1,3,3,3-Hexafluoro-2-propanol.

Need 1,1,1,3,3,3-Hexafluoro-2-propanol in a specific grade or volume?