1,1,1,3,3,3-Hexafluoro-2-propanol
1,1,1,3,3,3-Hexafluoro-2-propanol (CAS: 920-66-1), with the molecular formula (CF₃)₂CHOH and a molecular weight of 168.04 g/mol, is a unique fluorinated alcohol. It serves as a versatile solvent and a critical building block in organic synthesis. Its distinct properties make it valuable in specialised chemical research and the development of advanced materials.
- IUPAC
- HFP,Hexafluoroisopropanol
- Synonyms
- 3,3,3-Hexafluoro-2-propanol(CF3)2CHOHHFPHexafluoroisopropanol

Polymer Synthesis
1,1,1,3,3,3-Hexafluoro-2-propanol is employed in the preparation of hexafluoroalcohol-functionalized methacrylate polymers. These polymers are utilised in lithographic and nanopatterning materials.
Specialty Solvent
Its unique polarity and hydrogen-bonding capabilities make it a useful solvent for dissolving challenging substrates and in specific reaction media.
Organic Synthesis Intermediate
As a fluorinated alcohol, it acts as a key building block in the synthesis of complex organic molecules and pharmaceutical intermediates.
| Molecular weight | 168.04 |
|---|---|
| Linear formula | (CF3)2CHOH |
| Assay | ≥99.5% |
| Boiling point | 59 °C(lit.) |
| Density | 1.596 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.275(lit.) |
| Application | 1,1,1,3,3,3-Hexafluoro-2-propanol was used for preparing hexafluoroalcohol-functionalized methacrylate polymers for lithographic/nanopatterning materials1. |
| Melting point | −4 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) |
|---|---|
| Transport (UN / ADR) | UN 2922 8/PG 2 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | C |
| Risk statements (R) | 20/22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,1,1,3,3,3-Hexafluoro-2-propanol used for?
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1,1,1,3,3,3-Hexafluoro-2-propanol is used as a specialty solvent and a building block in organic synthesis, particularly for preparing functionalized polymers used in lithography and nanopatterning.
What are the CAS number and chemical formula for 1,1,1,3,3,3-Hexafluoro-2-propanol?
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The CAS number is 920-66-1, and the chemical formula is (CF₃)₂CHOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,1,1,3,3,3-Hexafluoro-2-propanol with an assay of ≥99.5%. We do not represent this product as USP, BP, or EP grade.
How should 1,1,1,3,3,3-Hexafluoro-2-propanol be handled safely?
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This compound is classified as corrosive and harmful if swallowed or inhaled. Handling requires appropriate personal protective equipment, including gloves, goggles, and respiratory protection, and should be done in a well-ventilated area. Refer to the safety data sheet for full details.
Does Tech Serve Solutions export 1,1,1,3,3,3-Hexafluoro-2-propanol?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 1,1,1,3,3,3-Hexafluoro-2-propanol.
How can I request a quote or sample for 1,1,1,3,3,3-Hexafluoro-2-propanol?
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Please contact our sales team via the website or phone to request a quote or sample for 1,1,1,3,3,3-Hexafluoro-2-propanol.
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