2-chloro-3-fluoro-4-(trifluoromethyl)pyridine
2-chloro-3-fluoro-4-(trifluoromethyl)pyridine (CAS: 628692-22-8, Formula: C6H2ClF4N) is a fluorinated pyridine derivative with a molecular weight of 199.53 g/mol. This compound serves as a valuable building block in organic synthesis, particularly for the introduction of trifluoromethyl-substituted pyridine moieties. Its unique structure lends itself to applications in the development of novel agrochemicals and pharmaceuticals, where precise functionalisation is key.

Agrochemical Intermediate
Utilised in the synthesis of active ingredients for crop protection products. The trifluoromethyl group often enhances biological activity and metabolic stability in pesticides and herbicides.
Pharmaceutical Building Block
Serves as a key intermediate in the discovery and development of new drug candidates. The fluorinated pyridine core is a common feature in many biologically active molecules.
Research and Development
Employed in academic and industrial research labs for exploring novel chemical reactions and constructing complex organic molecules with specific properties.
| Molecular weight | 199.53 |
|---|---|
| Empirical formula | C6H2ClF4N |

Hazard statements
- H300Fatal if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
| Flash point | >110 °C / >230 °F |
|---|---|
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-chloro-3-fluoro-4-(trifluoromethyl)pyridine used for?
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2-chloro-3-fluoro-4-(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly for agrochemicals and pharmaceuticals, and in research and development.
What are the CAS number and chemical formula for this compound?
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The CAS number is 628692-22-8 and the chemical formula is C6H2ClF4N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and chemical synthesis. The specific assay and grade available will be confirmed upon inquiry. We do not represent this product as USP, BP, or EP grade.
How should 2-chloro-3-fluoro-4-(trifluoromethyl)pyridine be handled safely?
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This compound is classified as Danger, indicated by GHS06. It is harmful if swallowed (H300), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area.
How is this chemical exported and shipped?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals. Details on packaging and shipping for 2-chloro-3-fluoro-4-(trifluoromethyl)pyridine, adhering to UN 2810 6.1 / PGIII regulations, can be provided upon request.
How can I request a quote or sample?
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To request a quote or a sample of 2-chloro-3-fluoro-4-(trifluoromethyl)pyridine, please contact our sales team through the website or by phone.
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