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2-ethynylthiophene

CAS 4298-52-6C6H4SChemical Synthesis

2-Ethynylthiophene (CAS: 4298-52-6), a thiophene derivative with the chemical formula C6H4S and a molecular weight of 108.16 g/mol, serves as a valuable heterocyclic building block in organic synthesis. Its reactive ethynyl group allows for versatile chemical transformations, making it a key intermediate for constructing more complex molecules. This compound is primarily utilised in chemical research and development, contributing to the advancement of novel materials and pharmaceuticals.

IUPAC
2-Acetylenylthiophene
Synonyms
2-Acetylenylthiophene
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2-ethynylthiophene (C6H4S) — chemical structure, CAS 4298-52-6; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC4 to C6Chemical SynthesisHeterocyclic Building BlocksThiophenes
01 /Applications

Organic Synthesis Intermediate

2-Ethynylthiophene acts as a foundational component in multi-step organic syntheses. Its terminal alkyne functionality readily participates in coupling reactions, cycloadditions, and functional group interconversions to build complex molecular architectures.

Pharmaceutical Research

This thiophene derivative is employed in medicinal chemistry for the development of novel pharmaceutical agents. Its incorporation into target molecules can influence pharmacokinetic properties and biological activity.

Materials Science

The compound can be a precursor in the synthesis of conjugated polymers and organic electronic materials. The thiophene ring and ethynyl group contribute to unique electronic and optical properties.

02 /Properties
Molecular weight108.16
Empirical formulaC6H4S
Assay90%
Density1.139 g/mL at 25 °C
Refractive indexn20/D 1.580
Storage temperature−20°C
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
Warning

Hazard statements

  • H226Flammable liquid and vapour
Flash point42 °C / 107.6 °F
Transport (UN / ADR)UN 1993C 3 / PGIII
Water hazard class (WGK, DE)3
Risk statements (R)10

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
4298-52-6
MDL number
MFCD03425129
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Ethynylthiophene used for?

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2-Ethynylthiophene is primarily used as a building block in organic synthesis, particularly in the fields of pharmaceutical research and materials science for creating complex molecules and functional materials.

What is the CAS number and formula for 2-Ethynylthiophene?

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The CAS number for 2-Ethynylthiophene is 4298-52-6, and its chemical formula is C6H4S.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Ethynylthiophene with a minimum assay of 90%. We do not represent this product as meeting USP, BP, EP, or other pharmacopoeial standards; it is suitable for research and technical applications.

How should 2-Ethynylthiophene be handled safely?

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2-Ethynylthiophene is a flammable liquid and vapour (H226). Handle with care in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment. Store at -20°C as indicated.

How is 2-Ethynylthiophene packed and shipped?

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2-Ethynylthiophene is packed and shipped according to relevant transportation regulations (UN 1993, Class 3, PGIII). Tech Serve Solutions exports globally, ensuring compliance with international shipping standards.

How can I request a quote or sample for 2-Ethynylthiophene?

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To request a quote or sample for 2-Ethynylthiophene, please contact our sales department via the website or direct inquiry, providing your specific requirements and delivery details.

Need 2-ethynylthiophene in a specific grade or volume?