1-(4-Fluorophenyl)pyrrolidin-3-one
1-(4-Fluorophenyl)pyrrolidin-3-one (CAS 536742-69-5) is a fluorinated heterocyclic building block with the molecular formula C10H10FNO and a molar mass of 179.19 g/mol. It pairs a 3-oxo-pyrrolidine ring with a 4-fluorophenyl group on the ring nitrogen, giving a reactive ketone handle valued in pharmaceutical and fine-chemical synthesis. Tech Serve Solutions supplies it as a research-grade intermediate to laboratories and manufacturers worldwide, with documentation and consistent quality for development programmes.
- Synonyms
- 1-(4-Fluorophenyl)pyrrolidin-3-one1-(4-fluorophenyl)-3-pyrrolidinone1-(4-fluorophenyl)tetrahydro-1H-pyrrol-3(2H)-one3-Pyrrolidinone, 1-(4-fluorophenyl)-CAS 536742-69-5
Pharmaceutical intermediate
Serves as a fluorinated pyrrolidinone building block in the synthesis of drug candidates and pharmaceutical intermediates. The 3-keto group offers a versatile site for further functionalisation.
Fluorinated heterocyclic building block
Used in medicinal-chemistry programmes where a 4-fluorophenyl substituent and a saturated nitrogen heterocycle are required. Fluorine substitution is commonly introduced to modulate metabolic stability and binding.
Ketone for reductive and condensation chemistry
The pyrrolidin-3-one carbonyl is a reactive handle for reductive amination, reduction to the corresponding alcohol, and condensation reactions, enabling access to substituted 3-aminopyrrolidine and 3-hydroxypyrrolidine scaffolds.
Research and discovery chemistry
Applied in laboratory-scale exploratory synthesis and structure-activity studies where a compact, fluorine-bearing pyrrolidinone core is needed to build screening libraries.
| Molecular weight | 179.19 |
|---|---|
| Empirical formula | C10H10FNO |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(4-Fluorophenyl)pyrrolidin-3-one used for?
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It is used as a fluorinated heterocyclic building block in chemical synthesis, principally as an intermediate in pharmaceutical and fine-chemical research. Its reactive 3-keto group supports reductive amination, reduction and condensation to build substituted pyrrolidine scaffolds.
What is the CAS number and molecular formula of 1-(4-Fluorophenyl)pyrrolidin-3-one?
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The CAS number is 536742-69-5 and the molecular formula is C10H10FNO, corresponding to a molecular weight of 179.19 g/mol.
What grade and purity does Tech Serve Solutions supply?
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We supply 1-(4-Fluorophenyl)pyrrolidin-3-one as a research/technical-grade synthesis intermediate with a certificate of analysis for each batch. We do not represent it as USP, BP or EP pharmacopoeial grade. Current assay specifications can be confirmed on request when you enquire.
How should 1-(4-Fluorophenyl)pyrrolidin-3-one be handled and stored?
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Handle as a research chemical not intended for medicinal, household or other unapproved use. Use suitable personal protective equipment, work with adequate ventilation, and avoid contact with skin and eyes and any dust formation. Store in a tightly closed container in a cool, dry, well-ventilated place away from incompatible materials. Refer to the accompanying Safety Data Sheet before use; full handling and hazard details are provided with each shipment.
How is 1-(4-Fluorophenyl)pyrrolidin-3-one packed, shipped and exported?
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It is packed in appropriate laboratory and bulk containers, sealed and labelled for export, and accompanied by a certificate of analysis and Safety Data Sheet. As a specialist exporter, Tech Serve Solutions arranges compliant international shipping and documentation to suit your destination and quantity.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, and our team will provide a quotation, available specifications and lead time. Samples can be arranged for evaluation on request.
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