1-(4-Fluorophenyl)-5-methyl-1H-pyrazole-4-carboxaldehyde
1-(4-Fluorophenyl)-5-methyl-1H-pyrazole-4-carboxaldehyde (CAS 423768-41-6; C11H9FN2O; molar mass 204.20 g/mol) is a fluorinated pyrazole aldehyde used chiefly as a fine-chemical building block. Combining a reactive 4-formyl group with a 4-fluorophenyl-substituted, 5-methyl pyrazole ring, it serves as an intermediate in pharmaceutical, agrochemical and heterocyclic synthesis. Tech Serve Solutions supplies it as a research-grade reagent for laboratory and process chemistry.
- Synonyms
- 1-(4-Fluorophenyl)-5-methyl-1H-pyrazole-4-carboxaldehyde1-(4-Fluorophenyl)-5-methyl-1H-pyrazole-4-carbaldehyde1-(4-Fluorophenyl)-5-methylpyrazole-4-carbaldehyde5-Methyl-1-(4-fluorophenyl)-1H-pyrazole-4-carbaldehydeCAS 423768-41-6MFCD03407349
Pharmaceutical intermediate
Acts as a fluorinated heterocyclic building block in medicinal-chemistry and pharmaceutical synthesis programmes. The aldehyde and the pre-formed pyrazole core allow elaboration toward more complex drug-like scaffolds.
Reactive aldehyde for synthesis
The 4-carbaldehyde group undergoes typical aldehyde transformations such as reductive amination, condensation, Wittig and Knoevenagel reactions, and reduction to the corresponding alcohol, making it a versatile handle for further functionalisation.
Fluorinated building block
The 4-fluorophenyl substituent introduces fluorine and aromatic character in a single step, a common strategy for tuning the metabolic stability, lipophilicity and binding of target molecules.
Heterocyclic and agrochemical research
Pyrazole carbaldehydes of this type are widely used scaffolds in the discovery of agrochemical and bioactive heterocyclic compounds. Use in such programmes is for research and development purposes.
Laboratory reference and reagent
Supplied as a defined organic reagent for use in analytical, method-development and exploratory laboratory work where a characterised fluorinated pyrazole aldehyde is required.
| Molecular weight | 204.20 |
|---|---|
| Empirical formula | C11H9FN2O |
| Melting point | 111-117 °C |
Hazard statements
- H315Causes skin irritation
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 38 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(4-Fluorophenyl)-5-methyl-1H-pyrazole-4-carboxaldehyde used for?
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It is used mainly as a fine-chemical building block and synthetic intermediate. The reactive 4-formyl group and fluorinated pyrazole ring make it useful in pharmaceutical, agrochemical and heterocyclic synthesis, and in laboratory research. Specific downstream uses depend on the customer's own programme.
What is the CAS number and molecular formula of 1-(4-Fluorophenyl)-5-methyl-1H-pyrazole-4-carboxaldehyde?
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Its CAS number is 423768-41-6 and its molecular formula is C11H9FN2O, with a molecular weight of 204.20 g/mol. The MDL number is MFCD03407349 and the reported melting point is 111-117 °C.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a technical/research-grade reagent for laboratory and process use. We do not represent it as USP, BP or EP pharmacopoeial grade. A current Certificate of Analysis stating the actual assay and batch specifications is available on request before purchase.
What are the safety and handling requirements?
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The product is classified GHS07 with the signal word Warning and hazard statement H315 (causes skin irritation). Avoid skin contact, wear suitable protective gloves and eyewear, and handle in a well-ventilated area. The German Water Hazard Class is WGK 3 (severely hazardous to water), so prevent release to drains and the environment. Always consult the Safety Data Sheet before use.
How is 1-(4-Fluorophenyl)-5-methyl-1H-pyrazole-4-carboxaldehyde packed, shipped and exported?
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It is packed as a solid in appropriately sealed, labelled containers sized from gram research quantities up to larger bulk orders. Shipments are accompanied by full documentation, including a Certificate of Analysis and Safety Data Sheet, and are exported worldwide in accordance with applicable transport and customs regulations.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, and our team will respond with availability, lead time and a formal quotation. Samples can be arranged for evaluation, subject to availability and regulatory requirements.
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