1-(4-Chlorophenyl)piperazine dihydrochloride
1-(4-Chlorophenyl)piperazine dihydrochloride (CAS 38869-46-4) is the crystalline dihydrochloride salt of 4-chlorophenylpiperazine, with molecular formula C10H13ClN2 · 2HCl and a molar mass of 269.60 g/mol. It is an N-arylpiperazine building block used in organic and medicinal-chemistry synthesis. Tech Serve Solutions supplies it as a research-grade reagent (assay 95%) for laboratory and pharmaceutical-intermediate use. It is offered to qualified buyers worldwide for synthesis and analytical reference applications.
- Synonyms
- 1-(4-Chlorophenyl)piperazine dihydrochloride4-Chlorophenylpiperazine dihydrochloridepCPP dihydrochloridepara-Chlorophenylpiperazine dihydrochloride1-(4-Chlorophenyl)piperazine 2HClCAS 38869-46-4
Heterocyclic building block
Serves as an N-arylpiperazine scaffold in chemical synthesis, where the secondary piperazine nitrogen is alkylated, acylated or coupled to construct more elaborate molecules.
Pharmaceutical intermediate
The 4-chlorophenylpiperazine motif is widely used in medicinal-chemistry programmes. This dihydrochloride salt is supplied as an intermediate for research and development under appropriate regulatory controls.
Analytical reference material
4-Chlorophenylpiperazine (mCPP's positional isomer, the para-substituted compound) is a documented metabolite of certain marketed drugs, so the well-characterised salt is useful as a reference standard in method development and quality control.
Medicinal-chemistry research
Used in laboratory studies exploring structure-activity relationships across arylpiperazine chemotypes. Specific biological applications should be defined and validated by the end user.
| Molecular weight | 269.60 |
|---|---|
| Empirical formula | C10H13ClN2 · 2HCl |
| Assay | 95% |
| Melting point | 275-278 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(4-Chlorophenyl)piperazine dihydrochloride used for?
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It is used mainly as a heterocyclic building block and pharmaceutical intermediate. The 4-chlorophenylpiperazine scaffold is functionalised at the free piperazine nitrogen to build larger target molecules, and the salt also serves as an analytical reference material in research settings.
What is the CAS number and molecular formula of 1-(4-Chlorophenyl)piperazine dihydrochloride?
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The CAS number is 38869-46-4 and the molecular formula is C10H13ClN2 · 2HCl, corresponding to a molecular weight of 269.60 g/mol. Related identifiers include EC number 254-165-0 and MDL number MFCD00012766.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research/technical-grade reagent with a typical assay of 95%. We do not represent it as USP, BP or EP pharmacopoeia grade. A current specification or certificate of analysis can be provided with each batch on request.
What are the safety and handling requirements?
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It is classified GHS07 with the signal word Warning and hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Wear gloves, eye protection and an N95-type dust mask, avoid dust formation, and follow the precautionary advice P261 and P305+P351+P338. It carries German Water Hazard Class WGK 3, so prevent release to the environment.
How is 1-(4-Chlorophenyl)piperazine dihydrochloride packed, shipped and exported?
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It is packed as a solid in sealed, labelled containers sized to the order, from research quantities upward, with full documentation including a GHS-compliant safety data sheet and certificate of analysis. Tech Serve Solutions exports worldwide and arranges compliant transport and any import or end-use documentation required for your destination.
Is this a controlled or scheduled substance?
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The supplied data does not list a scheduling status for this compound. Because arylpiperazines can be regulated in some jurisdictions, buyers are responsible for confirming the import, possession and end-use rules in their country. Tech Serve Solutions supplies only to legitimate research, analytical and manufacturing users and may request end-use details.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination country, and our team will respond with availability, lead time and documentation. Quote the product name or CAS 38869-46-4 to ensure an accurate response.
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