1-(4-Fluorobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid
1-(4-Fluorobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid (CAS 618070-43-2) is a fluorinated heterocyclic building block supplied as a solid with a melting point of 194-198 °C. With the molecular formula C12H11FN2O3 and a molecular weight of 250.23 g/mol, it combines a 4-fluorobenzyl-substituted pyrazole ring with a free carboxylic acid handle. Tech Serve Solutions offers it at 97% assay for research and chemical-synthesis applications, principally as an intermediate in medicinal-chemistry and pharmaceutical discovery programmes.
- Synonyms
- 1-(4-Fluorobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid1-[(4-fluorophenyl)methyl]-3-methyl-1H-pyrazole-5-carboxylic acid1-(4-fluorobenzyl)-3-methylpyrazole-5-carboxylic acidCAS 618070-43-2MFCD03933282
Heterocyclic building block
Serves as a versatile pyrazole scaffold for the synthesis of more complex molecules. The combined 4-fluorobenzyl group and carboxylic acid allow further functionalisation in multi-step routes.
Pharmaceutical and medicinal-chemistry intermediate
Used in discovery chemistry as an intermediate toward candidate compounds. The free carboxylic acid is a convenient point for amide coupling, esterification and related derivatisation.
Fluorinated building block
The 4-fluorobenzyl substituent introduces a fluorine atom that chemists frequently use to modulate the metabolic stability and physicochemical properties of target molecules.
Reference and research-scale synthesis
Supplied at 97% assay for laboratory research, method development and small-scale synthetic work where a defined pyrazole carboxylic acid is required.
| Molecular weight | 250.23 |
|---|---|
| Empirical formula | C12H11FN2O3 |
| Assay | 97% |
| Melting point | 194-198 °C(lit.) |
Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(4-Fluorobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid used for?
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It is used mainly as a fluorinated heterocyclic building block and synthetic intermediate in medicinal chemistry and pharmaceutical research. The pyrazole ring and free carboxylic acid make it suitable for amide coupling, esterification and further functionalisation in multi-step synthesis.
What is the CAS number and molecular formula of 1-(4-Fluorobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid?
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The CAS number is 618070-43-2. As supplied, the molecular formula is C12H11FN2O3 with a molecular weight of 250.23 g/mol. Its MDL number is MFCD03933282 and the reported melting point is 194-198 °C.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at 97% assay as a research and technical-grade chemical for synthesis and laboratory use. We do not represent it as USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each batch on request.
What are the safety and handling requirements?
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The product is classified under GHS07 with the signal word Warning and the hazard statement H319 (causes serious eye irritation). Handle with eye protection and gloves, avoid contact with the eyes, and use a suitable respirator filter (type N95/P1) where dust may form. If in eyes, rinse cautiously with water for several minutes (P305+P351+P338). It carries a German Water Hazard Class (WGK) of 3. Always consult the Safety Data Sheet before use.
How is 1-(4-Fluorobenzyl)-3-methyl-1H-pyrazole-5-carboxylic acid packed, shipped and exported?
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It is packed as a solid in sealed, labelled containers sized to the order, from gram quantities to bulk, with full documentation. Tech Serve Solutions has exported fine chemicals and intermediates since 1998 and arranges compliant international shipping with the relevant safety paperwork and certificate of analysis.
How do I request a sample or quote?
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Send an enquiry to Tech Serve Solutions with your required quantity, purity and delivery destination, and our team will respond with availability, lead time and a quotation. Samples can be arranged for evaluation where appropriate.
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