1-(4-Fluoro-2-methylphenyl)piperidin-4-one
1-(4-Fluoro-2-methylphenyl)piperidin-4-one (CAS 938458-77-6) is a fluorinated N-aryl piperidin-4-one with the molecular formula C12H14FNO and a molar mass of 207.24 g/mol. It pairs a 4-fluoro-2-methylphenyl group on the piperidine nitrogen with a reactive 4-oxo (ketone) function. This heterocyclic building block is used mainly in chemical synthesis and medicinal-chemistry research. Tech Serve Solutions supplies it as a research-grade material to laboratories worldwide.
- Synonyms
- 1-(4-Fluoro-2-methylphenyl)piperidin-4-one1-(4-fluoro-2-methylphenyl)-4-piperidinone1-(4-fluoro-2-methylphenyl)-4-piperidone4-fluoro-2-methylphenyl piperidin-4-oneCAS 938458-77-6

Heterocyclic building block
Serves as an N-aryl piperidin-4-one scaffold in multi-step organic synthesis, providing a defined fluorinated framework on which further chemistry can be built.
Reactive ketone intermediate
The 4-oxo group supports common transformations such as reductive amination, reduction to the corresponding alcohol, and condensation reactions, making the molecule a versatile synthetic handle.
Fluorinated motif for medicinal chemistry
The 4-fluoro-2-methylphenyl substituent introduces fluorine and steric character valued in structure-activity studies and lead-compound exploration during drug-discovery research.
Research and laboratory use
Used by research, analytical and process-development laboratories as a reference and starting material for the preparation of more complex piperidine derivatives.
| Molecular weight | 207.24 |
|---|---|
| Empirical formula | C12H14FNO |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(4-Fluoro-2-methylphenyl)piperidin-4-one used for?
+
It is used primarily as a fluorinated heterocyclic building block in organic and medicinal-chemistry synthesis. The reactive 4-ketone allows reductive amination, reduction and condensation, while the 4-fluoro-2-methylphenyl group provides a useful fluorinated motif for research applications.
What is the CAS number and molecular formula of 1-(4-Fluoro-2-methylphenyl)piperidin-4-one?
+
The CAS number is 938458-77-6. The molecular formula is C12H14FNO (Hill notation), corresponding to a molecular weight of 207.24 g/mol.
What grade and purity does Tech Serve Solutions supply?
+
We supply this compound as a research/technical-grade building block for synthesis and laboratory use. We do not represent it as USP, BP or EP pharmacopoeial grade. A current Certificate of Analysis stating the actual assay and batch details is provided with each lot on request.
How should 1-(4-Fluoro-2-methylphenyl)piperidin-4-one be handled and stored?
+
Handle as a research chemical using good laboratory practice: wear suitable gloves, eye protection and a lab coat, avoid dust, contact and inhalation, and work with adequate ventilation. Store in a tightly closed container in a cool, dry, well-ventilated area away from incompatible materials. Always consult the accompanying Safety Data Sheet before use.
How is 1-(4-Fluoro-2-methylphenyl)piperidin-4-one packed, shipped and exported?
+
It is packed in securely sealed, appropriately labelled containers sized from gram-scale research quantities to larger volumes, with packaging matched to the order and destination. Tech Serve Solutions exports worldwide with full documentation, including a Certificate of Analysis and Safety Data Sheet, in line with applicable transport and customs requirements.
How do I request a sample or a quote?
+
Contact Tech Serve Solutions with your required quantity, packaging and delivery destination, and our team will respond with availability, lead time and a formal quotation. Samples can be arranged on request, subject to availability.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis