1-(4-Chlorophenyl)piperazine
1-(4-Chlorophenyl)piperazine (CAS 38212-33-8) is an arylpiperazine building block with the molecular formula C10H13ClN2 and a molar mass of 196.68 g/mol. Supplied as a solid (melting point 76–79 °C) at ≥98.0% (GC) purity, it serves chiefly as a heterocyclic intermediate in chemical synthesis and as a research-grade serotonergic ligand. Tech Serve Solutions supplies it worldwide to pharmaceutical, fine-chemical and laboratory customers for research and manufacturing use.
- Synonyms
- 1-(4-Chlorophenyl)piperazine4-ChlorophenylpiperazinepCPPpara-chlorophenylpiperazine1-(p-Chlorophenyl)piperazineN-(4-Chlorophenyl)piperazine
Pharmaceutical and fine-chemical intermediate
Used as an arylpiperazine building block in multi-step synthesis. The secondary amine and chloroaryl ring offer convenient handles for N-alkylation, acylation and further functionalisation toward more complex piperazine-containing molecules.
Heterocyclic building block
A versatile C10 piperazine scaffold for medicinal-chemistry and discovery programmes. It is widely employed in structure–activity studies built around the arylpiperazine core.
Serotonergic research ligand
1-(4-Chlorophenyl)piperazine is a documented arylpiperazine that interacts with serotonin (5-HT) receptor systems, making it a useful reference compound in receptor pharmacology and neuroscience research. Supplied for laboratory research use only.
Reference and analytical standard
Its defined identity (Beilstein 150981, MDL MFCD00044823) and ≥98.0% GC purity make it suitable as a characterised reference material for method development and analytical comparison.
| Molecular weight | 196.68 |
|---|---|
| Empirical formula | C10H13ClN2 |
| Assay | ≥98.0% (GC) |
| Melting point | 76-79 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Htr3a(79246) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(4-Chlorophenyl)piperazine used for?
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It is used mainly as an arylpiperazine building block in pharmaceutical and fine-chemical synthesis, and as a research-grade serotonergic ligand for receptor and neuroscience studies. It is supplied for research and manufacturing use, not for human or veterinary administration.
What is the CAS number and molecular formula of 1-(4-Chlorophenyl)piperazine?
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The CAS number is 38212-33-8 and the molecular formula is C10H13ClN2, with a molecular weight of 196.68 g/mol. Related identifiers include MDL number MFCD00044823 and Beilstein registry number 150981.
What grade and purity does Tech Serve Solutions supply?
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We supply 1-(4-Chlorophenyl)piperazine at a typical assay of ≥98.0% (GC) as a technical/research-grade material (melting point 76–79 °C). We do not represent it as USP, BP or EP pharmacopoeia grade. A certificate of analysis is provided with each batch.
What are the safety and handling requirements?
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It is classified under GHS07 with the signal word Warning and hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Avoid dust formation, use a type N95 dust mask, eye protection and gloves, and ensure good ventilation (P261, P305+P351+P338). It is assigned WGK 3 (highly hazardous to water) in Germany. Always consult the full Safety Data Sheet before use.
How is 1-(4-Chlorophenyl)piperazine packed, shipped and exported?
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It is packed as a solid in sealed, labelled containers sized from research quantities to bulk, with packaging selected to suit the order and destination. Each shipment includes a certificate of analysis and Safety Data Sheet, and we handle export documentation and compliant international dispatch for our global customers.
How do I request a sample or quote?
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Send us the grade, quantity and delivery destination you require through the enquiry form or by contacting Tech Serve Solutions directly. We will confirm availability, specifications, lead time and a quotation, along with the relevant documentation.
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