1-(4-Chlorophenyl)ethylamine
1-(4-Chlorophenyl)ethylamine (CAS 6299-02-1) is a chiral benzylic primary amine with the molecular formula ClC6H4CH(NH2)CH3 and a molecular weight of 155.62. Supplied as a clear liquid of around 97% assay, it features a stereogenic carbon bearing an amino group adjacent to a 4-chlorophenyl ring. It is used principally as an organic building block and intermediate in chemical synthesis and as a chiral auxiliary or resolving agent in research applications.
- Synonyms
- 1-(4-Chlorophenyl)ethylamine(4-Chlorophenyl)ethylaminealpha-Methyl-4-chlorobenzylamine1-(4-Chlorophenyl)ethanamine4-Chloro-alpha-methylbenzylamine4-Chloro-alpha-methylbenzenemethanaminep-Chloro-alpha-methylbenzylamineCAS 6299-02-1
Organic building block
Serves as a versatile C8 nitrogen building block for the construction of more complex molecules. The reactive primary amine readily undergoes acylation, reductive amination, sulfonylation and condensation reactions.
Pharmaceutical and fine-chemical intermediate
Functions as an intermediate in multi-step synthesis routes within research and fine-chemical settings. The 4-chlorophenyl group offers a useful handle for further functionalisation.
Chiral auxiliary and resolving agent
As a chiral primary amine available in racemic and enantiopure forms, it is employed in asymmetric synthesis and in the resolution of racemic acids through diastereomeric salt formation.
Ligand and amide synthesis
Used to prepare chiral amides, imines and amine-based ligands for studies in coordination chemistry and stereoselective transformations.
Laboratory reagent
Applied as a reference amine and reagent in method development and exploratory synthesis where a substituted alpha-methylbenzylamine scaffold is required.
| Molecular weight | 155.62 |
|---|---|
| Linear formula | ClC6H4CH(NH2)CH3 |
| Assay | 97% |
| Density | 1.080 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.543(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 102 °C / 215.6 °F |
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(4-Chlorophenyl)ethylamine used for?
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It is used mainly as an organic building block and synthetic intermediate, and as a chiral auxiliary or resolving agent in research. The primary amine and 4-chlorophenyl ring make it a flexible scaffold for acylation, reductive amination and the preparation of chiral amides and ligands.
What is the CAS number and molecular formula of 1-(4-Chlorophenyl)ethylamine?
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The CAS number is 6299-02-1 and the molecular formula is ClC6H4CH(NH2)CH3, with a molecular weight of 155.62. Further identifiers include EC number 228-576-0 and MDL number MFCD00044766.
What grade and purity does Tech Serve Solutions supply?
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We supply 1-(4-Chlorophenyl)ethylamine at approximately 97% assay as a technical/research-grade reagent. We do not represent it as USP, BP or EP pharmacopoeial grade. A certificate of analysis is provided with each batch, and specifications can be confirmed against your requirements on request.
What are the safety and handling requirements?
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It is classified GHS05 with the signal word Danger and hazard statement H314 (causes severe skin burns and eye damage). Handle only with suitable gloves, goggles or face shield and respiratory protection, avoid all contact with skin and eyes, and consult the Safety Data Sheet before use. In case of contact, rinse cautiously with water and seek medical attention.
How is 1-(4-Chlorophenyl)ethylamine packed, shipped and exported?
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It is packed in tightly sealed, corrosion-resistant containers appropriate to the order quantity and labelled to GHS standards. As a corrosive material it is transported under UN 2735, Class 8, Packing Group II, with documentation and packaging compliant with applicable transport regulations. We export worldwide with full shipping paperwork.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will respond with availability, lead time and a formal quotation. Samples can be arranged where appropriate, subject to transport rules for corrosive goods.
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