1-(4-Chlorophenyl)biguanide hydrochloride
1-(4-Chlorophenyl)biguanide hydrochloride (CAS 4022-81-5) is an aryl-substituted biguanide supplied as the hydrochloride salt, with the linear formula ClC6H4NHC(NH)NHC(NH)NH2 · HCl and a molecular weight of 248.11 g/mol. It is a crystalline organic building block belonging to the guanidine family. The compound is used principally in research-scale chemical synthesis as a nitrogen-rich intermediate, notably for constructing triazine and related heterocyclic systems. Tech Serve Solutions supplies it to laboratory and manufacturing customers worldwide.
- Synonyms
- 1-(4-Chlorophenyl)biguanide hydrochloride4-Chlorophenylbiguanide hydrochlorideN-(4-Chlorophenyl)biguanide hydrochlorideN-(4-Chlorophenyl)imidodicarbonimidic diamide hydrochloride1-(4-Chlorophenyl)biguanide HCl
Heterocyclic building block
The biguanide moiety is a classic precursor to 1,3,5-triazine and diaminotriazine ring systems. This makes the compound a useful nitrogen-rich building block in chemical synthesis.
Guanidine-based intermediate
As a substituted biguanide bearing a 4-chlorophenyl group, it serves as an intermediate for preparing further functionalised guanidine and aminoheterocycle derivatives in research settings.
Pharmaceutical and agrochemical research
Biguanides are a well-documented scaffold in medicinal and agrochemical discovery chemistry. This reagent supports exploratory synthesis where an aryl-biguanide motif is required.
Laboratory reagent
Supplied at 97% assay, it is suited to bench-scale reactions, method development and the preparation of reference materials by research chemists.
| Molecular weight | 248.11 |
|---|---|
| Linear formula | ClC6H4NHC(NH)NHC(NH)NH2 · HCl |
| Assay | 97% |
| Melting point | 239-242 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(4-Chlorophenyl)biguanide hydrochloride used for?
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It is used mainly as a research-grade organic building block in chemical synthesis. The aryl-biguanide structure is a recognised precursor to triazine and other nitrogen heterocycles, and it serves as an intermediate in pharmaceutical and agrochemical discovery chemistry.
What is the CAS number and molecular formula of 1-(4-Chlorophenyl)biguanide hydrochloride?
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The CAS number is 4022-81-5. The linear formula is ClC6H4NHC(NH)NHC(NH)NH2 · HCl, with a molecular weight of 248.11 g/mol. Its MDL number is MFCD00053020.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a typical assay of 97%, as a research and technical grade reagent. We do not represent it as USP, BP or EP pharmacopoeial grade. Batch-specific certificates of analysis can be provided on request.
What are the safety and handling requirements?
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It is classified under GHS07 with the signal word Warning. The hazard statements are H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves, eye protection and an N95-type dust mask, avoid generating dust, and follow precautionary statements P261 and P305+P351+P338. Always consult the Safety Data Sheet before use.
How is 1-(4-Chlorophenyl)biguanide hydrochloride packed, shipped and exported?
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It is packed as a solid in suitably sealed containers sized to the order, with full labelling and documentation. Tech Serve Solutions exports worldwide and can prepare the SDS and shipping paperwork appropriate to your destination and chosen transport mode.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and delivery location, and our team will respond with availability, lead time and a formal quotation. Samples can be arranged for evaluation where applicable.
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