1-(3-Phenyl-2-propenoyl)-1H-1,2,3-benzotriazole
1-(3-Phenyl-2-propenoyl)-1H-1,2,3-benzotriazole (CAS 26112-94-7) is an N-acylbenzotriazole reagent with the molecular formula C15H11N3O and a molar mass of 249.27 g/mol. It is the benzotriazole-activated derivative of cinnamic acid (a cinnamoyl benzotriazolide), supplied as a crystalline solid melting at 157-161 °C. As a stable, easily handled acyl-transfer reagent, it is used principally in synthetic chemistry for C-C and C-N bond formation, cinnamoylation and related acylation reactions.
- Synonyms
- 1-(3-Phenyl-2-propenoyl)-1H-1,2,3-benzotriazole1-Cinnamoyl-1H-benzotriazole1-(Cinnamoyl)benzotriazole(E)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-phenylprop-2-en-1-oneN-cinnamoylbenzotriazoleCAS 26112-94-7C15H11N3O
Cinnamoylation and acyl transfer
Acts as a stable, isolable cinnamoyl donor, transferring the 3-phenyl-2-propenoyl (cinnamoyl) group to amines, alcohols and other nucleophiles under mild conditions as an alternative to acid chlorides or anhydrides.
C-C bond formation
Employed as a synthetic reagent in carbon-carbon bond-forming sequences, where the benzotriazole leaving group activates the carbonyl toward controlled addition and substitution.
Amide and ester synthesis
Used to prepare cinnamamides and cinnamate esters, giving clean conversions with benzotriazole released as a readily separable by-product.
Building block for heterocycles and conjugates
Serves as an activated cinnamoyl building block in multistep synthesis, including the construction of nitrogen heterocycles and enone-containing intermediates.
Research and laboratory reagent
Applied in research and development settings as a benchtop-stable acylating reagent that simplifies handling compared with more moisture-sensitive activated acids.
| Molecular weight | 249.27 |
|---|---|
| Empirical formula | C15H11N3O |
| Assay | 97% |
| Melting point | 157-161 °C(lit.) |
Hazard statements
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3-Phenyl-2-propenoyl)-1H-1,2,3-benzotriazole used for?
+
It is used in synthetic chemistry as an N-acylbenzotriazole acyl-transfer reagent. It delivers the cinnamoyl (3-phenyl-2-propenoyl) group to nucleophiles such as amines and alcohols to form cinnamamides and cinnamate esters, and it serves as a reagent for C-C and C-N bond formation in research and development.
What is the CAS number and molecular formula of 1-(3-Phenyl-2-propenoyl)-1H-1,2,3-benzotriazole?
+
The CAS number is 26112-94-7 and the molecular formula is C15H11N3O, with a molecular weight of 249.27 g/mol. The MDL number is MFCD00426339, and the material melts at approximately 157-161 °C.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound at a typical assay of 97% as a research and laboratory reagent grade. We do not represent it as USP, BP or EP pharmacopoeial grade. A current Certificate of Analysis is provided with each batch, and exact specifications can be confirmed at the time of enquiry.
What are the safety and handling requirements for this compound?
+
It is classified GHS05 with the signal word Danger and hazard statement H318 (causes serious eye damage). Wear protective gloves and eye or face protection. If it enters the eyes, rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, and continue rinsing (P280, P305+P351+P338). It carries WGK 3 (German water hazard class), so prevent release to drains and watercourses. Always consult the Safety Data Sheet before use.
How is 1-(3-Phenyl-2-propenoyl)-1H-1,2,3-benzotriazole packed, shipped and exported?
+
It is packed as a solid in tightly sealed, appropriately labelled containers sized from research quantities to bulk, with packaging selected to suit the order and destination. Tech Serve Solutions ships and exports worldwide with full documentation, including the Certificate of Analysis and Safety Data Sheet. Packing and transport details are confirmed at the time of order.
How do I request a sample or quote?
+
Contact Tech Serve Solutions with the product name, CAS number 26112-94-7 and your required quantity and grade. We will respond with availability, lead time, documentation and a formal quotation, and can arrange a sample where appropriate.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis