ATPA

CAS 83654-14-2C10H16N2O4Cell Biology

(RS)-2-Amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl)propanoic acid (ATPA), CAS 83654-14-2, is a non-proteinogenic amino acid with the molecular formula C10H16N2O4 and a molecular weight of 228.25 g/mol. This compound functions as a potent agonist for AMPA and kainate receptors. Its primary applications are within neuroscience research, specifically for studying excitatory amino acid neurotransmission and ionotropic glutamate receptors.

IUPAC: (RS)-2-Amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl)propanoic acid
Synonyms: (RS)-2-Amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl)propanoic acid

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ATPA (C10H16N2O4) — chemical structure, CAS 83654-14-2; Life Science, fine chemical supplied by Tech Serve Solutions

AMPA/Kainate AgonistsAN-AZBioactive Small MoleculesCell BiologyExcitatory Amino AcidsIon ChannelsLigand-Gated Ion ChannelsNeuroscienceNeurotransmissionNeurotransmitters More...

01 /Applications

Neuroscience Research Tool

ATPA is utilized as a pharmacological tool to investigate the function and modulation of AMPA and kainate receptors in the central nervous system. It helps researchers understand excitatory neurotransmission.

Study of Glutamate Receptors

As a specific agonist, ATPA aids in the characterisation of ionotropic glutamate receptor subtypes, including their signalling pathways and roles in synaptic plasticity and neuronal excitability.

Cellular Signaling Investigations

Researchers employ ATPA to probe cellular responses mediated by glutamate receptor activation, contributing to a deeper understanding of cell signalling mechanisms in neuronal networks.

02 /Properties

Molecular weight	228.25
Empirical formula	C10H16N2O4
Form	solid
Colour	white
Solubility	DMSO: soluble10 mg/mLH2O: soluble2.5 mg/mL

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

83654-14-2

MDL number

MFCD01860864

PubChem substance

24277951

05 /Additional specifications

Gene Information	human ... GRIK1(2897)rat ... Gria1(50592), Grik1(29559), Grin2a(24409)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is ATPA used for?

ATPA is primarily used as a research tool in neuroscience to study the function of AMPA and kainate receptors, investigate excitatory amino acid neurotransmission, and characterise ionotropic glutamate receptor subtypes.

What are the CAS number and molecular formula for ATPA?

The CAS number for ATPA is 83654-14-2, and its molecular formula is C10H16N2O4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies ATPA as a research-grade chemical. The purity is not specified in the provided data, and TSS does not represent it as USP, BP, or EP grade.

What are the safety precautions for handling ATPA?

When handling ATPA, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It has a WGK Germany rating of 3, indicating it is hazardous to water.

Is ATPA a controlled substance?

The provided data does not indicate that ATPA is a controlled substance.

How is ATPA packaged, shipped, and exported by TSS?

Tech Serve Solutions, as a specialist global supplier and exporter of fine chemicals, packages, ships, and exports ATPA in accordance with international regulations for chemical products.