Atractylenolide III
Atractylenolide III (CAS: 73030-71-4) is a sesquiterpenoid phytochemical with the molecular formula C15H20O3 and a molecular weight of 248.32 g/mol. This compound is utilised in research for its potential anti-inflammatory and anti-angiogenesis properties. It may also serve as an inhibitor of aromatases, an inducer of apoptosis, and a tool to investigate sonic hedgehog pathway-dependent chondrogenic differentiation.
- IUPAC
- 8β-Hydroxyasterolide,Codonolactone
- Synonyms
- 8β-Hydroxyasterolide, Codonolactone
Anti-inflammatory and Anti-angiogenesis Research
Atractylenolide III is employed in scientific studies to investigate its potential roles in modulating inflammatory responses and inhibiting angiogenesis, a process crucial in various disease states.
Aromatase Inhibition and Apoptosis Induction
Researchers utilise Atractylenolide III to explore its capacity to act as an inhibitor of aromatase enzymes and as an agent that can induce programmed cell death (apoptosis).
Chondrogenic Differentiation Studies
This compound can be used to study mechanisms of chondrogenic differentiation, particularly focusing on its action within the sonic hedgehog pathway.
Reference Standard
Atractylenolide III serves as a valuable reference material for analytical assays, aiding in the quantification of its presence in natural plant extracts and biological samples like plasma.
| Molecular weight | 248.32 |
|---|---|
| Empirical formula | C15H20O3 |
| Assay | ≥98% (HPLC) |
| Solubility | methanol: soluble1 mg/mL, clear, colorless |
| Storage temperature | 2-8°C |
| Application | Atractylenolide III, a sesquiterpenoid, is a phytochemical that may be used to study its anti-inflammatory and anti-angiogenesis activities. Atractylenolide III may be used and studied as an inhibitor of aromatases and inducer of apoptosis. Atractylenolide III may be used to study its sonic hedgehog pathway dependent mechanism of action as an inducer of chondrogenic differentiation. Atractylenolide III may be used as a reference material in assays to detect its presence in plant root extracts and biological milieu such as plasma. |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Atractylenolide III used for?
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Atractylenolide III is used in research for studying its anti-inflammatory, anti-angiogenesis, aromatase inhibitory, and apoptosis-inducing activities, as well as its role in chondrogenic differentiation. It also serves as a reference standard.
What are the CAS number and formula for Atractylenolide III?
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The CAS number for Atractylenolide III is 73030-71-4, and its molecular formula is C15H20O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Atractylenolide III with a purity of ≥98% as determined by HPLC. This product is intended for research purposes and is not supplied as USP, BP, EP, or other pharmacopoeial grades.
How should Atractylenolide III be handled and stored?
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Atractylenolide III should be stored at 2-8°C. Due to its classification with a WGK (German water hazard class) of 3, appropriate safety precautions should be taken during handling to avoid environmental release.
Is Atractylenolide III a controlled substance?
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The provided data does not indicate that Atractylenolide III is a controlled substance.
How can I request a sample or quote for Atractylenolide III?
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To request a sample or a quote for Atractylenolide III, please contact the Tech Serve Solutions sales team through our website or by phone.
How is Atractylenolide III shipped?
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Atractylenolide III is exported and shipped according to standard chemical handling and transportation regulations, typically under refrigerated conditions (2-8°C).
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