1-(3-Methylphenyl)piperazine
1-(3-Methylphenyl)piperazine (CAS 41186-03-2; molecular formula C11H16N2; molar mass 176.26 g/mol), also known as 1-(m-tolyl)piperazine, is an aryl-substituted piperazine building block. It is typically a liquid to low-melting solid bearing a basic, secondary piperazine nitrogen at the meta-toluidine ring. Tech Serve Solutions supplies it as a research-grade fine chemical at ≥97.5% (HPLC) for organic synthesis and medicinal-chemistry programmes where a substituted-arylpiperazine scaffold is required.
- IUPAC
- 1-(m-Tolyl)piperazine
- Synonyms
- 1-(3-Methylphenyl)piperazine1-(m-Tolyl)piperazinem-tolylpiperazine3-methylphenylpiperazine1-(3-methylphenyl)-piperazine1-(3-methylphenyl)piperazine
Pharmaceutical and medicinal-chemistry intermediate
Serves as an arylpiperazine building block in the synthesis of candidate molecules and active pharmaceutical ingredient intermediates. The reactive secondary piperazine nitrogen is readily acylated, alkylated or coupled to extend more complex structures.
Heterocyclic building block
Used as a meta-tolyl-substituted piperazine scaffold for structure-activity studies and the assembly of nitrogen-containing heterocyclic frameworks. The defined methyl substitution position supports targeted regiochemistry in discovery chemistry.
Fine-chemical and custom synthesis
Applied as a reagent and intermediate in laboratory- and pilot-scale organic synthesis. The free piperazine NH allows condensation, reductive amination and N-functionalisation to access derivatives.
Research and reference reagent
Supplied for analytical, method-development and reference applications where a characterised arylpiperazine of known identity and assay is needed.
| Molecular weight | 176.26 |
|---|---|
| Empirical formula | C11H16N2 |
| Assay | ≥97.5% (HPLC)97.5-102.5% (T) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3-Methylphenyl)piperazine used for?
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It is used principally as an arylpiperazine building block and intermediate in organic synthesis and medicinal-chemistry research. The basic secondary piperazine nitrogen is readily functionalised, making the compound a versatile meta-tolyl scaffold for preparing more complex nitrogen-containing molecules.
What is the CAS number and molecular formula of 1-(3-Methylphenyl)piperazine?
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The CAS number is 41186-03-2 and the molecular formula is C11H16N2, with a molecular weight of 176.26 g/mol. It is also identified by EC number 255-251-0 and Beilstein registry number 140376, and is commonly called 1-(m-tolyl)piperazine.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(3-Methylphenyl)piperazine as a research-grade fine chemical with an assay of ≥97.5% by HPLC (97.5-102.5% by titration). It is offered for research and manufacturing use; we do not represent it as USP, BP or EP pharmacopoeial grade unless agreed in writing.
What are the safety and handling requirements?
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It is classified under GHS07 with the signal word Warning and hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Wear suitable protective gloves, eye protection and ensure adequate ventilation (P261, P305+P351+P338). It is assigned German Water Hazard Class WGK 3 (severely hazardous to water), so prevent release to drains and the environment. Always consult the Safety Data Sheet before use.
How is 1-(3-Methylphenyl)piperazine packed, shipped and exported?
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It is packed in appropriately sealed, labelled containers sized to order, from laboratory quantities to bulk, with each consignment accompanied by relevant documentation. As a global supplier and exporter, Tech Serve Solutions arranges compliant packaging, labelling and shipping in line with applicable transport and destination-country requirements.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and packaging, and we will respond with availability, lead time and a quotation. Sample requests for evaluation can be accommodated subject to availability and regulatory checks.
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