Trimethylsilyl trimethylsiloxyacetate
Trimethylsilyl trimethylsiloxyacetate (CAS 33581-77-0) is an ester with the linear formula (CH3)3SiOCH2CO2Si(CH3)3 and a molecular weight of 220.41 g/mol. This compound, offered by Tech Serve Solutions with a purity of 99%, is primarily utilised as a building block in chemical synthesis. Its properties make it suitable for specialised organic chemistry applications and the development of novel materials.

Synthesis of Organometallic Complexes
Trimethylsilyl trimethylsiloxyacetate serves as a precursor in the synthesis of complex organometallic compounds. For instance, it has been employed in the preparation of zirconium(IV) carboxylato complexes, showcasing its utility in advanced inorganic chemistry research.
Organic Building Block
As a versatile organic building block, this ester is valuable for constructing more complex molecular architectures. Its reactive silyl ether and ester functionalities allow for diverse transformations in synthetic organic chemistry pathways.
Chemical Synthesis Reagent
The compound is applied in various chemical synthesis procedures, acting as a reagent or intermediate. Its specific structure lends itself to reactions requiring ester or silyl ether functionalities.
| Molecular weight | 220.41 |
|---|---|
| Linear formula | (CH3)3SiOCH2CO2Si(CH3)3 |
| Assay | 99% |
| Density | 0.903 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.411(lit.) |
| Application | Trimethylsilyl trimethylsiloxyacetate has been used in the synthesis of zirconium(IV) carboxylato complexes [LOEtZr(OCOCH2OH)(O2CCH2O)]21. |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 35 °C / 95 °F |
| Transport (UN / ADR) | UN 3272 3 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trimethylsilyl trimethylsiloxyacetate used for?
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Trimethylsilyl trimethylsiloxyacetate is used as a building block in chemical synthesis, particularly in the preparation of organometallic complexes and for constructing complex molecular architectures in organic chemistry.
What is the CAS number and formula for Trimethylsilyl trimethylsiloxyacetate?
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The CAS number is 33581-77-0 and the linear formula is (CH3)3SiOCH2CO2Si(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trimethylsilyl trimethylsiloxyacetate with a purity of 99%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should Trimethylsilyl trimethylsiloxyacetate be handled safely?
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Trimethylsilyl trimethylsiloxyacetate is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, in a well-ventilated area away from ignition sources.
Is Trimethylsilyl trimethylsiloxyacetate packed and exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions, a specialist global supplier and exporter, packs and exports Trimethylsilyl trimethylsiloxyacetate worldwide.
How can I request a sample or quote for Trimethylsilyl trimethylsiloxyacetate?
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Please contact our sales team via the website or directly to request a sample or a quotation for Trimethylsilyl trimethylsiloxyacetate.
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