Trimethylsilyl propiolate
Trimethylsilyl propiolate (CAS: 19232-22-5), with the formula HC≡CCO₂Si(CH₃)₃ and a molecular weight of 142.23 g/mol, is a versatile organic building block. This ester compound is primarily utilised in chemical synthesis due to its reactive functional groups. It serves as a valuable intermediate in the creation of more complex molecules, finding applications in research and development across various chemical disciplines.
- IUPAC
- Trimethylsilyl acetylenecarboxylate
Organic Synthesis Intermediate
Trimethylsilyl propiolate is employed as a key building block in organic synthesis, enabling the construction of diverse carbon frameworks. Its structure facilitates participation in various coupling and addition reactions.
Research and Development
This compound is frequently used in academic and industrial research laboratories for exploring novel synthetic pathways and developing new chemical entities. Its specific reactivity profile makes it an attractive reagent for synthetic chemists.
Ester Chemistry
As a silyl ester, it participates in reactions characteristic of esters, offering a protected form of propiolic acid for specific synthetic strategies.
| Molecular weight | 142.23 |
|---|---|
| Linear formula | HC≡CCO2Si(CH3)3 |
| Assay | 97% |
| Boiling point | 70-75 °C(lit.) |
| Density | 0.925 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.416(lit.) |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 20 °C / 68 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34 |
| Safety statements (S) | 16-26-33-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trimethylsilyl propiolate used for?
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Trimethylsilyl propiolate is primarily used as a versatile building block in organic synthesis and in chemical research and development for creating complex molecules.
What is the CAS number and formula for Trimethylsilyl propiolate?
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The CAS number for Trimethylsilyl propiolate is 19232-22-5, and its formula is HC≡CCO₂Si(CH₃)₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trimethylsilyl propiolate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Trimethylsilyl propiolate be handled safely?
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Trimethylsilyl propiolate is a flammable liquid and causes severe skin burns and eye damage (H225, H314). Handle with appropriate personal protective equipment, including gloves, goggles, and respiratory protection, in a well-ventilated area, away from ignition sources.
Is Trimethylsilyl propiolate exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Trimethylsilyl propiolate.
How can I request a sample or quote for Trimethylsilyl propiolate?
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Please contact our sales team directly via our website or by phone to request a sample or a quotation for Trimethylsilyl propiolate.
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