Trimethylsilyl chlorosulfonate
Trimethylsilyl chlorosulfonate (CAS: 4353-77-9) is a chemical compound with the linear formula ClSO₃Si(CH₃)₃ and a molecular weight of 188.71 g/mol. This organosilicon compound serves as a valuable building block in organic synthesis. Its reactivity makes it useful for introducing the chlorosulfonyl group or silylating agents in various chemical transformations. It is primarily employed in research and development settings for creating complex molecules and novel materials.
Organic Synthesis Reagent
Trimethylsilyl chlorosulfonate is a versatile reagent used in organic synthesis for the introduction of sulfonyl chloride functionalities onto organic molecules. It can also act as a silylating agent under specific conditions, protecting hydroxyl or amine groups.
Intermediate in Chemical Manufacturing
This compound functions as an intermediate in the synthesis of various specialty chemicals. Its unique structure allows for tailored reactions in the development of pharmaceuticals, agrochemicals, and other fine chemical products.
Research and Development
Utilised in academic and industrial research laboratories, Trimethylsilyl chlorosulfonate aids in exploring new synthetic routes and developing novel compounds with potential applications across different scientific fields.
| Molecular weight | 188.71 |
|---|---|
| Linear formula | ClSO3Si(CH3)3 |
| Assay | ≥99.0% (AT) |
| Boiling point | 168-169 °C(lit.)62-64 °C/10 mmHg(lit.) |
| Density | 1.225 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.424(lit.) |
| Melting point | −26 °C(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 42 °C / 107.6 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trimethylsilyl chlorosulfonate used for?
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Trimethylsilyl chlorosulfonate is primarily used as a reagent in organic synthesis for introducing sulfonyl chloride groups and as a silylating agent. It serves as a valuable building block in the preparation of various fine chemicals and in research and development.
What is the CAS number and formula for Trimethylsilyl chlorosulfonate?
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The CAS number for Trimethylsilyl chlorosulfonate is 4353-77-9 and its linear formula is ClSO₃Si(CH₃)₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Trimethylsilyl chlorosulfonate with an assay of ≥99.0% (AT). This is a technical grade material, and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the main safety hazards associated with Trimethylsilyl chlorosulfonate?
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Trimethylsilyl chlorosulfonate is a flammable liquid and vapour (H226) and causes severe skin burns and eye damage (H314). It requires careful handling, appropriate personal protective equipment including gloves, eye protection, and respiratory protection, and should be stored away from ignition sources.
How is Trimethylsilyl chlorosulfonate packed and shipped?
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As a specialist global supplier, Tech Serve Solutions exports Trimethylsilyl chlorosulfonate. It is shipped according to relevant dangerous goods regulations (UN 2920, Class 3(8), Packing Group II) to ensure safe transport.
How can I request a sample or quote for Trimethylsilyl chlorosulfonate?
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To request a sample or a quote for Trimethylsilyl chlorosulfonate, please contact our sales team through the website or direct email, providing your specific requirements.
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