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3-(1-Hydroxyethyl)aniline

CAS 2454-37-7CH3CH(OH)C6H4NH2Chemical Synthesis

3-(1-Hydroxyethyl)aniline (CAS: 2454-37-7), with the molecular formula CH3CH(OH)C6H4NH2 and a molecular weight of 137.18 g/mol, is a valuable organic building block. This compound features both an amino and a hydroxyl functional group, making it versatile for chemical synthesis. It is primarily utilised in the development of complex organic molecules and pharmaceutical intermediates. Its structure allows for diverse reactions, positioning it as a key intermediate in various synthetic pathways.

IUPAC
1-(3-Aminophenyl)ethanol,3-Amino-α-methylbenzyl alcohol
Synonyms
1-(3-Aminophenyl)ethanol3-Amino-α-methylbenzyl alcohol
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3-(1-Hydroxyethyl)aniline (CH3CH(OH)C6H4NH2) — chemical structure, CAS 2454-37-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Amino AlcoholsBuilding BlocksChemical SynthesisOrganic Building BlocksOxygen Compounds
01 /Applications

Pharmaceutical Intermediate Synthesis

Utilised as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Its bifunctional nature allows for the introduction of specific pharmacophores into target drug molecules.

Organic Synthesis Reagent

Serves as a versatile reagent in organic chemistry for creating more complex molecular structures. The presence of both amine and alcohol groups enables a range of chemical transformations.

Material Science Applications

Can be employed in the development of specialised polymers and materials where its functional groups contribute to specific material properties.

02 /Properties
Molecular weight137.18
Linear formulaCH3CH(OH)C6H4NH2
Assay98%
Melting point66-69 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H332Harmful if inhaled
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)20/21/22-36/37/38
Safety statements (S)26-37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
2454-37-7
MDL number
MFCD00007798
PubChem substance
24895511
Beilstein registry
2802415
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-(1-Hydroxyethyl)aniline used for?

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3-(1-Hydroxyethyl)aniline is primarily used as an intermediate in organic synthesis, particularly for the development of pharmaceutical ingredients and complex organic molecules. It serves as a versatile building block due to its amino and hydroxyl functional groups.

What are the CAS number and formula for 3-(1-Hydroxyethyl)aniline?

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The CAS number for 3-(1-Hydroxyethyl)aniline is 2454-37-7, and its molecular formula is CH3CH(OH)C6H4NH2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 3-(1-Hydroxyethyl)aniline with an assay of 98%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.

How should 3-(1-Hydroxyethyl)aniline be handled safely?

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3-(1-Hydroxyethyl)aniline is a Warning substance that can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335), and may be harmful if inhaled (H332). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.

Is 3-(1-Hydroxyethyl)aniline a controlled substance?

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The provided safety data does not indicate that 3-(1-Hydroxyethyl)aniline is a scheduled or controlled substance.

How is 3-(1-Hydroxyethyl)aniline packed and exported?

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Tech Serve Solutions offers 3-(1-Hydroxyethyl)aniline in various pack sizes suitable for laboratory and industrial use, adhering to all relevant export regulations for chemical compounds.

How can I request a quote or sample?

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To request a quote or a sample of 3-(1-Hydroxyethyl)aniline, please contact our sales department via the website or by phone, providing your specific requirements.

Need 3-(1-Hydroxyethyl)aniline in a specific grade or volume?