Tech Serve Solutions

Trimethylsilyl trifluoroacetate

CAS 400-53-3CF3CO2Si(CH3)3Chemical Synthesis

Trimethylsilyl trifluoroacetate (CAS 400-53-3), molecular formula CF3CO2Si(CH3)3, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.

IUPAC
Trifluoroacetic acid trimethylsilyl ester
Trimethylsilyl trifluoroacetate
Building BlocksC2 to C5Carbonyl CompoundsChemical SynthesisEsters
01 /Properties
Molecular weight186.20
Linear formulaCF3CO2Si(CH3)3
Assay≥97.0% (T)
Boiling point88-90 °C(lit.)
Density1.078 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.336(lit.)n20/D 1.336
Vapour density>1 (vs air)
02 /Safety & handling
Flammable
Flammable
Corrosive
Corrosive
Danger

Hazard statements

  • H225Highly flammable liquid and vapour
  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point13 °C / 55.4 °F
Transport (UN / ADR)UN 2924 8(3) / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)F,C
Risk statements (R)11-34-37
Safety statements (S)16-26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

03 /Identifiers & registry
CAS number
400-53-3
MDL number
MFCD00000413
Beilstein registry
1773314
04 /Quality & supply

Documentation

Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is Trimethylsilyl trifluoroacetate?

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Trimethylsilyl trifluoroacetate (CAS 400-53-3), molecular formula CF3CO2Si(CH3)3, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.

What grades of Trimethylsilyl trifluoroacetate does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Trimethylsilyl trifluoroacetate in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.

What is the CAS number and molecular formula of Trimethylsilyl trifluoroacetate?

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Trimethylsilyl trifluoroacetate has CAS number 400-53-3 and molecular formula CF3CO2Si(CH3)3. Full specifications appear in the table above and in the Certificate of Analysis.

What is the typical minimum order quantity and lead time for Trimethylsilyl trifluoroacetate?

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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.

Do you provide a Certificate of Analysis (CoA) with each shipment?

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Yes. Every batch of Trimethylsilyl trifluoroacetate ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.

How should Trimethylsilyl trifluoroacetate be stored?

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Store Trimethylsilyl trifluoroacetate in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.

What is Trimethylsilyl trifluoroacetate used for?

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Trimethylsilyl trifluoroacetate is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.

How do I request a quote for Trimethylsilyl trifluoroacetate?

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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.

Need Trimethylsilyl trifluoroacetate in a specific grade or volume?

Request a quote