2-(3-Bromopropoxy)tetrahydro-2H-pyran
2-(3-Bromopropoxy)tetrahydro-2H-pyran (CAS: 33821-94-2) is a halogenated heterocyclic building block with the molecular formula C8H15BrO2 and a molecular weight of 223.11 g/mol. This bifunctional compound features a latent alcohol functionality that can be readily generated under aqueous acidic conditions. Its structure makes it valuable for introducing protected hydroxyl groups in organic synthesis, particularly within the pharmaceutical and fine chemical industries.
- IUPAC
- 1-Bromo-3-(tetrahydropyranyloxy)propane
Protecting Group Chemistry
The tetrahydropyran (THP) group serves as a robust protecting group for alcohols. It can be easily introduced and later removed under mild acidic conditions, facilitating multi-step syntheses.
Organic Synthesis Intermediate
As a bifunctional molecule, it enables the sequential introduction of different functionalities, making it a versatile intermediate in the construction of complex organic molecules.
Pharmaceutical Research
Its utility in controlled functionalisation makes it a useful building block for the synthesis of novel pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
| Molecular weight | 223.11 |
|---|---|
| Empirical formula | C8H15BrO2 |
| Assay | 98% |
| Boiling point | 64.5 °C/0.8 mmHg(lit.) |
| Density | 1.317 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.478(lit.) |
| Storage temperature | −20°C |
| Contains / stabiliser | potassium carbonate as stabilizer |
| Application | The latent alcohol functionality of this bifunctional building block can be generated using aqueous acid.1,2 |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 106 °C / 222.8 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(3-Bromopropoxy)tetrahydro-2H-pyran used for?
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This compound is primarily used as a bifunctional building block in organic synthesis, particularly for introducing protected alcohol functionalities. The tetrahydropyran (THP) group can be readily removed under aqueous acidic conditions to reveal the alcohol.
What are the CAS number and formula for 2-(3-Bromopropoxy)tetrahydro-2H-pyran?
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The CAS number is 33821-94-2, and the empirical formula is C8H15BrO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(3-Bromopropoxy)tetrahydro-2H-pyran with an assay of 98%. This product is suitable for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
What are the safety precautions when handling 2-(3-Bromopropoxy)tetrahydro-2H-pyran?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a half-mask respirator. It has a flash point of 106 °C (222.8 °F), indicating it is combustible. Refer to the Safety Data Sheet for full handling guidelines.
How is 2-(3-Bromopropoxy)tetrahydro-2H-pyran packed, shipped, and exported?
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This chemical is carefully packed according to international regulations for safe transport. Tech Serve Solutions is an experienced global supplier and exporter, ensuring reliable delivery worldwide.
How can I request a sample or quote for 2-(3-Bromopropoxy)tetrahydro-2H-pyran?
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Please contact our sales team via the website or direct email to request a sample or obtain a quotation for 2-(3-Bromopropoxy)tetrahydro-2H-pyran.
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