(Trimethylsilyl)methanesulfonate
(Trimethylsilyl)methanesulfonate, CAS 10090-05-8, features the molecular formula H3CSO3OSi(CH3)3 and a molecular weight of 168.29 g/mol. This organosilicon compound serves as a versatile reagent in organic synthesis. Its primary applications involve facilitating reduction reactions, promoting dehydration for regioselective elimination, and enabling dealklysilylation in complex chemical processes, making it a valuable tool for synthetic chemists.
- IUPAC
- Methanesulfonic acid trimethylsilyl ester,Trimethylsilyl mesylate
- Synonyms
- Methanesulfonic acid trimethylsilyl esterTrimethylsilyl mesylate
Reduction of Esters to Ethers
(Trimethylsilyl)methanesulfonate acts as a key reagent in the reduction of esters to ethers, specifically utilising boron difluoride triflate etherate as a catalyst. This reaction pathway offers an efficient method for synthesizing ether compounds.
Regioselective Dehydration
This compound facilitates the elimination of C(8)-functional groups through regioselective dehydration. This application is crucial for controlling the stereochemistry and position of functional groups during synthetic transformations.
Dealklysilylation Reactions
It is employed in the dealklysilylation of alumazene derivatives. This process is significant in organometallic chemistry and the synthesis of specific silicon-containing compounds.
| Molecular weight | 168.29 |
|---|---|
| Linear formula | H3CSO3OSi(CH3)3 |
| Boiling point | 103-104 °C/25 mmHg(lit.) |
| Density | 1.09 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.422(lit.)n20/D 1.422 |
| Application | Reactant or reagent involved in:• Reduction of esters to ethers using boron difluoride triflate etherate1• Elimination of C(8)-functional groups via regioselective dehydration2• Dealkylsilylation of alumazene derivatives3 |
Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 30 °C / 86 °F |
| Transport (UN / ADR) | UN 3272 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 10 |
| Safety statements (S) | 23-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Trimethylsilyl)methanesulfonate used for?
+
(Trimethylsilyl)methanesulfonate is used as a reagent in organic synthesis, including the reduction of esters to ethers, regioselective dehydration for elimination reactions, and dealklysilylation of alumazene derivatives.
What is the CAS number and chemical formula for (Trimethylsilyl)methanesulfonate?
+
The CAS number is 10090-05-8 and the chemical formula is H3CSO3OSi(CH3)3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (Trimethylsilyl)methanesulfonate at a purity suitable for research and synthetic applications. For specific batch analysis and purity details, please refer to the Certificate of Analysis.
How should (Trimethylsilyl)methanesulfonate be handled safely?
+
(Trimethylsilyl)methanesulfonate is a flammable liquid and vapour (H226). Handle in a well-ventilated area, away from ignition sources. Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be worn. Avoid contact with eyes and skin. Refer to the Safety Data Sheet for comprehensive handling information.
How is (Trimethylsilyl)methanesulfonate packed, shipped, and exported?
+
(Trimethylsilyl)methanesulfonate is packed and shipped according to international regulations for hazardous materials, including UN 3272. Tech Serve Solutions offers global export services for this chemical.
How can I request a sample or quote for (Trimethylsilyl)methanesulfonate?
+
To request a sample or a detailed quote for (Trimethylsilyl)methanesulfonate, please contact our sales team through the website or directly via email, providing your specific requirements and delivery location.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis