2-Amino-4-(trifluoromethyl)benzenethiol hydrochloride
2-Amino-4-(trifluoromethyl)benzenethiol hydrochloride (CAS: 4274-38-8), with the molecular formula C7H6F3NS · HCl, is a specialized organic building block. This compound, featuring a trifluoromethyl group and a thiol functionality, is primarily utilised in chemical synthesis. Its structural characteristics make it valuable for constructing complex molecules, particularly in the fields of medicinal chemistry and materials science. Tech Serve Solutions supplies this chemical for research and development purposes.

Organic Synthesis Intermediate
This compound serves as a versatile intermediate in organic synthesis. The presence of the amine, thiol, and trifluoromethyl groups allows for diverse chemical transformations.
Medicinal Chemistry Research
It is employed in the development of novel pharmaceutical agents. The trifluoromethyl group can influence pharmacokinetic properties, while the thiol group offers a site for conjugation or further functionalization.
Materials Science Applications
The unique electronic and structural properties of trifluoromethylated aromatic compounds make them of interest in materials science research, potentially for use in functional materials.
| Molecular weight | 229.65 |
|---|---|
| Linear formula | H2NC6H3(CF3)SH · HCl |
| Assay | 97% |
| Melting point | 196-198 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-4-(trifluoromethyl)benzenethiol hydrochloride used for?
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2-Amino-4-(trifluoromethyl)benzenethiol hydrochloride is used as an intermediate in organic synthesis, particularly in medicinal chemistry research and potentially in materials science applications.
What are the CAS number and chemical formula for this product?
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The CAS number is 4274-38-8 and the chemical formula is C7H6F3NS · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. This product is supplied for laboratory and research use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should 2-Amino-4-(trifluoromethyl)benzenethiol hydrochloride be handled safely?
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This compound is a Warning substance that is harmful if swallowed, in contact with skin, and if inhaled. It also causes skin irritation, serious eye irritation, and respiratory irritation. Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn. Handle in a well-ventilated area or fume hood.
Can Tech Serve Solutions export this chemical globally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Amino-4-(trifluoromethyl)benzenethiol hydrochloride.
How can I request a quote or sample?
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To request a quote or sample for 2-Amino-4-(trifluoromethyl)benzenethiol hydrochloride, please contact our sales team through the website or by phone.
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