2-Amino-4-(trifluoromethyl)pyrimidine
2-Amino-4-(trifluoromethyl)pyrimidine (CAS 16075-42-6, C5H4F3N3) is a fluorinated heterocyclic organic compound with a molecular weight of 163.10 g/mol. This chemical building block is valuable in synthetic organic chemistry, particularly for the construction of more complex molecules. Its structure incorporates both an amine group and a trifluoromethyl moiety on a pyrimidine ring, offering versatile reactivity for diverse chemical syntheses.

Pharmaceutical Intermediate
Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. The trifluoromethyl group often enhances metabolic stability and lipophilicity in target molecules.
Agrochemical Synthesis
Utilised in the development of novel pesticides, herbicides, and fungicides. Its unique structural features can contribute to the efficacy and selectivity of agrochemical products.
Materials Science
Incorporated into the design of functional organic materials. The presence of fluorine can influence electronic properties and intermolecular interactions.
Research and Development
A versatile reagent for academic and industrial research laboratories exploring new synthetic methodologies and novel compound discovery.
| Molecular weight | 163.10 |
|---|---|
| Empirical formula | C5H4F3N3 |
| Assay | 97% |
| Melting point | 174-178 °C |



Hazard statements
- H300Fatal if swallowed
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P273Avoid release to the environment
- P301IF SWALLOWED
- P305IF IN EYES
- P342
| Transport (UN / ADR) | UN 2811 6.1/PG 1 |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 25-36-43-50 |
| Safety statements (S) | 26-36/37-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-4-(trifluoromethyl)pyrimidine used for?
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2-Amino-4-(trifluoromethyl)pyrimidine is primarily used as a building block in chemical synthesis, particularly in the pharmaceutical and agrochemical industries for the development of new compounds. It is also employed in materials science research.
What are the CAS number and chemical formula for this product?
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The CAS number for 2-Amino-4-(trifluoromethyl)pyrimidine is 16075-42-6, and its chemical formula is C5H4F3N3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-4-(trifluoromethyl)pyrimidine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-Amino-4-(trifluoromethyl)pyrimidine be handled?
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This compound is classified as acutely toxic (H300), causes serious eye irritation (H319), and may cause allergy or asthma symptoms or breathing difficulties if inhaled (H334). It is also very toxic to aquatic life (H400). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid inhalation and contact with skin and eyes.
Is this product shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and we can arrange for the export of 2-Amino-4-(trifluoromethyl)pyrimidine.
How can I request a sample or quote?
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To request a sample or a quote for 2-Amino-4-(trifluoromethyl)pyrimidine, please contact our sales team through the website or by phone.
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