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2-Amino-4-(trifluoromethyl)pyrimidine

CAS 16075-42-6C5H4F3N3Chemical Synthesis

2-Amino-4-(trifluoromethyl)pyrimidine (CAS 16075-42-6, C5H4F3N3) is a fluorinated heterocyclic organic compound with a molecular weight of 163.10 g/mol. This chemical building block is valuable in synthetic organic chemistry, particularly for the construction of more complex molecules. Its structure incorporates both an amine group and a trifluoromethyl moiety on a pyrimidine ring, offering versatile reactivity for diverse chemical syntheses.

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2-Amino-4-(trifluoromethyl)pyrimidine (C5H4F3N3) — chemical structure, CAS 16075-42-6; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC4 to C5Chemical SynthesisHeterocyclic Building BlocksPyrimidines
01 /Applications

Pharmaceutical Intermediate

Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. The trifluoromethyl group often enhances metabolic stability and lipophilicity in target molecules.

Agrochemical Synthesis

Utilised in the development of novel pesticides, herbicides, and fungicides. Its unique structural features can contribute to the efficacy and selectivity of agrochemical products.

Materials Science

Incorporated into the design of functional organic materials. The presence of fluorine can influence electronic properties and intermolecular interactions.

Research and Development

A versatile reagent for academic and industrial research laboratories exploring new synthetic methodologies and novel compound discovery.

02 /Properties
Molecular weight163.10
Empirical formulaC5H4F3N3
Assay97%
Melting point174-178 °C
03 /Safety & handling
GHS hazard pictogram: Toxic (GHS06)
Toxic
GHS hazard pictogram: Health hazard (GHS08)
Health hazard
GHS hazard pictogram: Environmental hazard (GHS09)
Environmental hazard
Danger

Hazard statements

  • H300Fatal if swallowed
  • H319Causes serious eye irritation
  • H334May cause allergy or asthma symptoms if inhaled
  • H400Very toxic to aquatic life

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P264Wash thoroughly after handling
  • P273Avoid release to the environment
  • P301IF SWALLOWED
  • P305IF IN EYES
  • P342
Transport (UN / ADR)UN 2811 6.1/PG 1
Water hazard class (WGK, DE)3
Hazard codes (EU)T,N
Risk statements (R)25-36-43-50
Safety statements (S)26-36/37-45-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
16075-42-6
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Amino-4-(trifluoromethyl)pyrimidine used for?

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2-Amino-4-(trifluoromethyl)pyrimidine is primarily used as a building block in chemical synthesis, particularly in the pharmaceutical and agrochemical industries for the development of new compounds. It is also employed in materials science research.

What are the CAS number and chemical formula for this product?

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The CAS number for 2-Amino-4-(trifluoromethyl)pyrimidine is 16075-42-6, and its chemical formula is C5H4F3N3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Amino-4-(trifluoromethyl)pyrimidine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.

How should 2-Amino-4-(trifluoromethyl)pyrimidine be handled?

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This compound is classified as acutely toxic (H300), causes serious eye irritation (H319), and may cause allergy or asthma symptoms or breathing difficulties if inhaled (H334). It is also very toxic to aquatic life (H400). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid inhalation and contact with skin and eyes.

Is this product shipped internationally?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and we can arrange for the export of 2-Amino-4-(trifluoromethyl)pyrimidine.

How can I request a sample or quote?

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To request a sample or a quote for 2-Amino-4-(trifluoromethyl)pyrimidine, please contact our sales team through the website or by phone.

Need 2-Amino-4-(trifluoromethyl)pyrimidine in a specific grade or volume?