(S)-5-(Hydroxymethyl)-2-pyrrolidinone
(S)-5-(Hydroxymethyl)-2-pyrrolidinone (CAS: 17342-08-4, C5H9NO2) is a chiral building block with a molecular weight of 115.13 g/mol. This heterocyclic compound is primarily utilised in asymmetric synthesis and chemical synthesis. It serves as a key intermediate in the preparation of specific amino acid derivatives and chiral ligands for enantioselective catalysis, offering precise stereochemical control in complex chemical transformations.
- IUPAC
- L-Pyroglutaminol
- Synonyms
- L-Pyroglutaminol
Synthesis of Diaminovaleric Acids
This compound is a precursor in the synthesis of (R)- and (S)-diaminovaleric acids, important chiral amino acids.
Preparation of Chiral Ligands
It is employed in the creation of 5-azasemicorrin bidentate nitrogen ligands, which are valuable tools for enantioselective catalysis.
Chiral Building Block
Utilised as a versatile chiral building block in asymmetric synthesis due to its defined stereochemistry.
Heterocyclic Chemistry
Serves as a useful intermediate in the synthesis of various pyrrolidine derivatives and other heterocyclic compounds.
| Molecular weight | 115.13 |
|---|---|
| Empirical formula | C5H9NO2 |
| Assay | 97% |
| Optical activity | [α]20/D +30°, c = 2 in ethanol |
| Application | Serves as a building block in the synthesis of (R)- and (S)-diaminovaleric acids1 and of 5-azasemicorrin bidentate nitrogen ligands for enantioselective catalysis.2 |
| Melting point | 79-80 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-5-(Hydroxymethyl)-2-pyrrolidinone used for?
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(S)-5-(Hydroxymethyl)-2-pyrrolidinone is used as a building block in asymmetric synthesis, chemical synthesis, and in the preparation of chiral ligands and specific amino acids like (R)- and (S)-diaminovaleric acids.
What is the CAS number and formula for (S)-5-(Hydroxymethyl)-2-pyrrolidinone?
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The CAS number is 17342-08-4 and the empirical formula is C5H9NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-5-(Hydroxymethyl)-2-pyrrolidinone with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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This compound is a Warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate PPE including a dust mask (type N95 US), eyeshields, and gloves should be used. Handle in a well-ventilated area.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (S)-5-(Hydroxymethyl)-2-pyrrolidinone.
How can I request a sample or a quote?
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To request a sample or a quote for (S)-5-(Hydroxymethyl)-2-pyrrolidinone, please contact our sales department through the website or by phone.
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