Bisantrene dihydrochloride
Bisantrene dihydrochloride (CAS: 78186-34-2; Formula: C22H22N8 ·2HCl) is a synthetic anthracenedicarboxaldehyde derivative. This compound is recognised for its role as an intercalating agent and topoisomerase II inhibitor, making it a valuable tool in biological research. It is primarily employed in studies related to apoptosis, cell cycle regulation, and DNA metabolism, contributing to advancements in molecular and cell biology.
- IUPAC
- Bis((4,5-dihydro-1H-imidazol-2-yl)hydrazone)-9,10-anthracenedicarboxaldehyde dihydrochloride,NSC 337766
Apoptosis and Cell Cycle Research
Bisantrene dihydrochloride serves as a key reagent in investigating programmed cell death pathways and cell cycle progression. Its mechanism of action aids researchers in understanding the complex regulatory networks governing cellular fate.
DNA Repair and Metabolism Studies
The compound is utilised in studies focused on DNA repair mechanisms and metabolic processes. Its interaction with DNA provides insights into cellular responses to damage and replication.
Cell Signaling Investigations
Researchers employ Bisantrene dihydrochloride to probe cellular signaling cascades, particularly those involved in cell proliferation and differentiation. This application supports the study of fundamental biological processes.
| Molecular weight | 471.39 |
|---|---|
| Empirical formula | C22H22N8 ·2HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Solubility | deionized water: soluble8 mg/mL |
| Storage temperature | room temp |
Hazard statements
- H302Harmful if swallowed
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-50/53 |
| Safety statements (S) | 60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bisantrene dihydrochloride used for?
+
Bisantrene dihydrochloride is primarily used in research for investigating apoptosis, cell cycle regulation, DNA repair, DNA metabolism, and cellular signaling pathways. It acts as an intercalating agent and topoisomerase II inhibitor.
What are the CAS number and formula for Bisantrene dihydrochloride?
+
The CAS number for Bisantrene dihydrochloride is 78186-34-2, and its formula is C22H22N8 ·2HCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Bisantrene dihydrochloride with a purity of ≥98% (HPLC). This product is intended for research purposes, and TSS does not represent it as USP, BP, or EP grade.
What are the safety considerations when handling Bisantrene dihydrochloride?
+
Bisantrene dihydrochloride is classified with GHS07 and GHS09 symbols, indicating it is harmful if swallowed (H302) and very toxic to aquatic life (H400). Handle with appropriate personal protective equipment in a well-ventilated area, and avoid release into the environment (P273).
How is Bisantrene dihydrochloride packed, shipped, and exported?
+
Bisantrene dihydrochloride is carefully packed to maintain its integrity during transit. As a specialist global supplier, Tech Serve Solutions expertly handles the export of this chemical, adhering to all relevant regulations for safe and compliant international shipment.
How can I request a sample or quote for Bisantrene dihydrochloride?
+
To request a sample or a quote for Bisantrene dihydrochloride, please contact our sales team through the website or call us directly. Our representatives will be pleased to assist you with your inquiry.
▶ Related products
(−)-Curcumol
C15H24O2
Cell Biology
(±) Clopidogrel hydrogensulfate
Cell Biology
(±)-L-Alliin
C6H11NO3S
Cell Biology
(±)-2-Amino-4-phosphonobutyric acid
C4H10NO5P
Cell Biology
(±)-2-Methylarachidonoyl-2′-fluoroethylamide
C23H38NOF
Cell Biology
(±)-3,4-Methylenedioxy-N-ethylamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxyamphetamine hydrochloride
Cell Biology
(±)-3,4-Methylenedioxymethamphetamine hydrochloride
Cell Biology
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis