(S)-5-(Bromomethyl)-2-pyrrolidinone

CAS 72479-05-1C5H8BrNOChemical Synthesis

(S)-5-(Bromomethyl)-2-pyrrolidinone (CAS 72479-05-1) is a chiral heterocyclic building block with a molecular weight of 178.03 g/mol. This compound is primarily employed in asymmetric synthesis and general chemical synthesis due to its reactive bromomethyl group and chiral pyrrolidinone core. It serves as a valuable intermediate for constructing more complex chiral molecules in research and development settings.

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(S)-5-(Bromomethyl)-2-pyrrolidinone (C5H8BrNO) — chemical structure, CAS 72479-05-1; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksPyrrolidines

01 /Applications

Chiral Building Block

Utilised in the synthesis of enantiomerically pure compounds, where its defined stereochemistry is crucial for downstream applications in pharmaceuticals and agrochemicals.

Asymmetric Synthesis

Serves as a key starting material or intermediate in asymmetric reactions, enabling the stereoselective formation of new chiral centres.

Heterocyclic Chemistry

Incorporated into synthetic routes requiring the introduction of a chiral pyrrolidinone moiety into target molecules.

Pharmaceutical Intermediate

Acts as a precursor in the development of potential drug candidates, leveraging its structural features for medicinal chemistry research.

02 /Properties

Molecular weight	178.03
Empirical formula	C5H8BrNO
Assay	96%
Optical activity	[α]22/D −30.0°, c = 0.5 in ethanol
Storage temperature	2-8°C
Melting point	75-79 °C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES

Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22-36-43
Safety statements (S)	26-36/37

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

72479-05-1

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-5-(Bromomethyl)-2-pyrrolidinone used for?

(S)-5-(Bromomethyl)-2-pyrrolidinone is used as a chiral building block in asymmetric synthesis and heterocyclic chemistry, particularly as an intermediate in the development of pharmaceutical compounds.

What is the CAS number and formula for (S)-5-(Bromomethyl)-2-pyrrolidinone?

The CAS number is 72479-05-1 and the empirical formula is C5H8BrNO.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (S)-5-(Bromomethyl)-2-pyrrolidinone with an assay of 96%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.

How should (S)-5-(Bromomethyl)-2-pyrrolidinone be handled safely?

Handle with appropriate personal protective equipment, including gloves and eye protection, as it is harmful if swallowed, may cause an allergic skin reaction, and causes serious eye irritation (H302-H317-H319). Store at 2-8°C.