(S)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline
(S)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline (CAS: 148461-16-9) is a chiral phosphine-oxazoline ligand with the molecular formula C25H26NOP and a molecular weight of 387.45 g/mol. This compound is a key reagent in asymmetric synthesis, particularly valued for its efficacy as a privileged ligand in transition-metal catalysed reactions. It is supplied by Tech Serve Solutions with a purity of 97%.
- IUPAC
- (4S)-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-4,5-dihydrooxazole
![(S)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline (C25H26NOP) — chemical structure, CAS 148461-16-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F148461-16-9.png&w=3840&q=75)
Asymmetric Catalysis
This oxazoline-based phosphine ligand is widely employed in transition metal catalysis to achieve high enantioselectivity in various organic transformations. Its unique structure facilitates precise control over reaction stereochemistry.
Ligand for Metal Complexes
It serves as a crucial chiral ligand in the formation of catalytically active metal complexes. These complexes are instrumental in developing stereoselective synthetic routes for complex molecules.
Organic Synthesis Reagent
As a valuable building block in organic synthesis, it enables chemists to introduce chirality and phosphorus functionality into target molecules. It is particularly useful in palladium-catalysed cross-coupling reactions.
| Molecular weight | 387.45 |
|---|---|
| Empirical formula | C25H26NOP |
| Assay | 97% |
| Optical activity | [α]22/D -57.0°, c = 1 in chloroform |
| Storage temperature | −20°C |
| Melting point | 111-116 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline used for?
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(S)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline is primarily used as a chiral ligand in asymmetric catalysis and as a reagent in organic synthesis to achieve stereoselective transformations.
What are the CAS number and molecular formula for this compound?
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The CAS number is 148461-16-9, and the molecular formula is C25H26NOP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. It is supplied for research and development purposes and is not guaranteed to meet pharmacopoeia standards (e.g., USP, EP, BP).
How should (S)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A respirator filter suitable for type N95 (US) or type P1 (EN143) should be used if necessary. It has a melting point of 111-116 °C and should be stored at -20°C.
Is this chemical a controlled substance?
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The provided data does not indicate that this chemical is a controlled substance.
How is this product packed and shipped?
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This product is carefully packed to ensure safe transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a quote or sample?
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Please contact our customer service team through the TSS website to request a quote or a sample of (S)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline.
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