2-(2′-Di-tert-butylphosphine)biphenylpalladium(II) acetate
2-(2′-Di-tert-butylphosphine)biphenylpalladium(II) acetate (CAS: 577971-19-8; Formula: C22H29O2PPd; MW: 462.86) is a palladium(II) complex and a precatalyst. It is primarily utilised as a highly effective catalyst in homogeneous catalysis, particularly for facilitating the Buchwald-Hartwig amination reaction. This compound is a valuable reagent for organic synthesis, enabling the formation of carbon-nitrogen bonds.
- IUPAC
- Palladium, (acetato-ΚO) [2′-[bis (1,1 dimethylethyl) phosphino-ΚP] [1,1′-biphenyl]-2-yl ΚC]

Buchwald-Hartwig Amination Precatalyst
This palladium(II) acetate complex serves as an efficient precatalyst for the Buchwald-Hartwig amination reaction. It facilitates the formation of aryl amines and related nitrogen-containing compounds.
Homogeneous Palladium Catalysis
As a member of the palladacycle catalyst family, it is employed in various homogeneous catalytic processes. Its structure is well-suited for promoting cross-coupling reactions in organic synthesis.
Organic Synthesis Reagent
This compound is a key building block and catalyst precursor in complex organic synthesis. It aids in the construction of intricate molecular architectures through catalysed transformations.
| Molecular weight | 462.86 |
|---|---|
| Empirical formula | C22H29O2PPd |
| Assay | 97% |
| Application | Precatalyst for Buchwald-Hartwig amination reaction. |
| Melting point | 130-140 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(2′-Di-tert-butylphosphine)biphenylpalladium(II) acetate used for?
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This compound is primarily used as a precatalyst for the Buchwald-Hartwig amination reaction, a crucial process in organic synthesis for forming carbon-nitrogen bonds.
What is the CAS number and chemical formula for this product?
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The CAS number is 577971-19-8 and the chemical formula is C22H29O2PPd.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. It is suitable for research and synthesis applications. TSS does not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
What are the safety and handling considerations for this chemical?
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This compound requires the use of eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified with WGK Germany 3, indicating a high hazard to water.
How is this product typically shipped or exported?
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Tech Serve Solutions specialises in global supply and export of fine chemicals, including this palladium complex, adhering to all relevant shipping and customs regulations.
How can I request a quote or sample?
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Please contact our sales department directly via our website or listed phone number to request a quotation or a sample.
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