2-(2-Dicyclohexylphosphinophenyl)-1,3-dioxolane
2-(2-Dicyclohexylphosphinophenyl)-1,3-dioxolane (CAS 246158-59-8), with the molecular formula C21H31O2P and a molecular weight of 346.44 g/mol, is a specialised phosphine ligand. It is primarily utilised in catalysis, particularly for the preparation of palladium P,O-ligand-catalyst systems. These systems are employed in crucial Suzuki cross-coupling reactions, demonstrating its value in synthetic organic chemistry.
- IUPAC
- Dicyclohexyl(2-(1,3-dioxolan-2-yl)phenyl)phosphine
- Synonyms
- Dicyclohexyl(2-(1,3-dioxolan-2-yl)phenyl)phosphine

Suzuki Cross-Coupling Reactions
Serves as a key phosphine ligand for constructing palladium P,O-ligand catalysts. These catalysts are instrumental in facilitating Suzuki cross-coupling reactions, a vital tool in organic synthesis for forming carbon-carbon bonds.
Catalyst Development
This compound is used in the development and preparation of specific palladium-based catalytic systems. Its unique structure contributes to the efficacy of catalysts employed in complex chemical transformations.
Organic Synthesis
As a phosphine compound, it finds application in various organic synthesis methodologies where precise control over catalytic processes is required. It aids in the construction of complex molecular architectures.
| Molecular weight | 346.44 |
|---|---|
| Empirical formula | C21H31O2P |
| Assay | 97% |
| Application | • Ligand for preparation of palladium P,O-ligand-catalyst for Suzuki cross-coupling reactions1 |
| Melting point | 82-85 °C(lit.) |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(2-Dicyclohexylphosphinophenyl)-1,3-dioxolane used for?
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It is used as a ligand for preparing palladium P,O-ligand-catalyst systems, particularly effective in Suzuki cross-coupling reactions.
What are the CAS number and formula for this compound?
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The CAS number is 246158-59-8 and the molecular formula is C21H31O2P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a minimum purity of 97%. This product is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations?
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The compound carries the hazard statement H413 (May cause long lasting harmful effects to aquatic life). Recommended personal protective equipment includes eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter.
Is this compound a controlled substance?
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There is no information in the provided data to suggest this compound is a controlled substance.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, providing this compound for international shipment.
How can I request a sample or quote?
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Please contact Tech Serve Solutions directly through our website or sales channels to request a sample or a quotation for this product.
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