(Trimethylsilyl)methanol
(Trimethylsilyl)methanol (CAS: 3219-63-4) is an organosilicon compound with the linear formula (CH3)3SiCH2OH and a molecular weight of 104.22 g/mol. This flammable liquid serves as a valuable building block in organic synthesis. It is primarily utilised as a reagent and intermediate in the preparation of various organic compounds and silane derivatives, finding application in academic research and industrial chemical processes.
- IUPAC
- (Hydroxymethyl)trimethylsilane
- Synonyms
- (Hydroxymethyl)trimethylsilane

Organic Synthesis Reagent
(Trimethylsilyl)methanol is employed as a versatile reagent in organic chemistry. Its structure allows for the introduction of the trimethylsilylmethyl group into organic molecules, facilitating various synthetic transformations.
Intermediate in Silane Chemistry
This compound acts as an intermediate in the synthesis of more complex organosilicon compounds. It is useful for creating specialised silanes used in materials science and polymer chemistry.
Building Block for Specialty Chemicals
As a C2 to C6 building block, (Trimethylsilyl)methanol contributes to the construction of more intricate molecular architectures. It is particularly useful in the development of novel chemical entities.
| Molecular weight | 104.22 |
|---|---|
| Linear formula | (CH3)3SiCH2OH |
| Assay | 98% |
| Boiling point | 120-122 °C/754 mmHg(lit.) |
| Density | 0.826 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.419(lit.) |
| Storage temperature | 2-8°C |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 56 °C / 132.8 °F |
| Transport (UN / ADR) | UN 1987C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Trimethylsilyl)methanol used for?
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(Trimethylsilyl)methanol is used as a reagent and intermediate in organic synthesis, particularly for introducing the trimethylsilylmethyl group and in the preparation of specialised silanes.
What are the CAS number and chemical formula for (Trimethylsilyl)methanol?
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The CAS number for (Trimethylsilyl)methanol is 3219-63-4, and its linear formula is (CH3)3SiCH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (Trimethylsilyl)methanol with an assay of 98%. This is a research grade material and TSS does not represent it as USP, BP, or EP grade.
How should (Trimethylsilyl)methanol be handled safely?
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(Trimethylsilyl)methanol is a flammable liquid and an irritant. Handle with appropriate personal protective equipment, including eyeshields and gloves, in a well-ventilated area. Avoid contact with skin, eyes, and clothing, and prevent inhalation of vapours.
Is (Trimethylsilyl)methanol shipped internationally?
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Yes, Tech Serve Solutions exports (Trimethylsilyl)methanol globally to meet the demands of research and industrial clients.
How can I request a quote or sample?
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To request a quote or a sample of (Trimethylsilyl)methanol, please contact the TSS sales department through our website or by phone.
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