(Trimethylsilyl)methyllithium solution
(Trimethylsilyl)methyllithium solution (CAS: 1822-00-0, Linear Formula: (CH3)3SiCH2Li, MW: 94.16) is a highly reactive organolithium reagent supplied by Tech Serve Solutions. This solution, typically 1.0 M in pentane, is a powerful alkylating agent and is utilized in organic synthesis for introducing the trimethylsilylmethyl group. It plays a key role in the initiation of polymerization and copolymerization reactions, particularly with cyclosiloxanes, and in the alkylation of metal complexes.

Polymerization Initiation
This reagent initiates the polymerization and copolymerization of cyclosiloxanes. It serves as a crucial component in controlling the formation of specific polymer structures.
Organometallic Synthesis
It is employed to alkylate metal complexes, facilitating the synthesis of various organometallic compounds used in catalysis and materials science.
Alkylating Agent
As a potent nucleophile, (Trimethylsilyl)methyllithium solution is effective for the introduction of the trimethylsilylmethyl group onto various organic and inorganic substrates.
| Molecular weight | 94.16 |
|---|---|
| Linear formula | (CH3)3SiCH2Li |
| Boiling point | 35-36 °C |
| Density | 0.65 g/mL at 25 °C |
| Concentration | 1.0 M in pentane |
| Storage temperature | 2-8°C |
| Application | Initiates polymerization and copolymerization of cyclosiloxanes.1 Alkylates metal complexes.2 |





Hazard statements
- H224Extremely flammable liquid and vapour
- H304May be fatal if swallowed and enters airways
- H314Causes severe skin burns and eye damage
- H336May cause drowsiness or dizziness
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -49 °C / -56.2 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 1 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C,N |
| Risk statements (R) | 11-14-34-51/53-65-67 |
| Safety statements (S) | 16-26-36/37/39-45-61-62 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Trimethylsilyl)methyllithium solution used for?
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(Trimethylsilyl)methyllithium solution is used to initiate polymerization and copolymerization of cyclosiloxanes and to alkylate metal complexes. It serves as a powerful alkylating agent in organic synthesis.
What are the CAS number and formula for (Trimethylsilyl)methyllithium solution?
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The CAS number is 1822-00-0, and the linear formula is (CH3)3SiCH2Li.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (Trimethylsilyl)methyllithium solution at a concentration of 1.0 M in pentane. We do not represent this product as USP, BP, or EP grade; it is suitable for research and technical applications.
How should (Trimethylsilyl)methyllithium solution be handled and stored?
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(Trimethylsilyl)methyllithium solution is highly flammable and reacts violently with water, posing severe health hazards. It requires handling under an inert atmosphere, with appropriate personal protective equipment including face shields, gloves, and respirators. Store at 2-8°C.
Is (Trimethylsilyl)methyllithium solution available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (Trimethylsilyl)methyllithium solution, adhering to all international shipping regulations.
How can I request a quote or sample of (Trimethylsilyl)methyllithium solution?
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Please contact our sales team via our website or by phone to request a quote or a sample of (Trimethylsilyl)methyllithium solution.
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