(Trimethylsilyl)ketene
(Trimethylsilyl)ketene (CAS 4071-85-6) is an organosilicon compound with the linear formula (CH3)3SiCH=C=O and a molecular weight of 114.22 g/mol. This highly reactive ketene derivative is primarily utilised as a versatile building block in organic synthesis, particularly for the introduction of ketene functionalities into complex molecules. It serves as a valuable reagent in the development of novel pharmaceuticals and advanced materials, owing to its unique reactivity profile.
Organic Synthesis Reagent
(Trimethylsilyl)ketene serves as a key intermediate in various organic transformations. Its silyl group facilitates controlled reactions, making it ideal for constructing complex carbon skeletons and introducing carbonyl functionalities in a regioselective manner.
Pharmaceutical Intermediate
This compound is employed in the synthesis of diverse pharmaceutical agents. Its reactivity allows for the efficient formation of heterocyclic compounds and other complex structures relevant to drug discovery and development.
Materials Science
The unique chemical properties of (Trimethylsilyl)ketene make it a useful component in the development of novel polymers and functional materials. It can be incorporated into material frameworks to impart specific chemical or physical characteristics.
| Molecular weight | 114.22 |
|---|---|
| Linear formula | (CH3)3SiCH=C=O |
| Assay | 97% |
| Boiling point | 80-82 °C(lit.) |
| Density | 0.813 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.413(lit.) |
| Contains / stabiliser | copper as stabilizer |
Hazard statements
- H225Highly flammable liquid and vapour
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -16 °C / 3.2 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F |
| Risk statements (R) | 11 |
| Safety statements (S) | 7/9-16-29-33 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shelf Life | 1‑2 mo. (in freezer) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (Trimethylsilyl)ketene primarily used for?
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(Trimethylsilyl)ketene is primarily used as a versatile building block and reagent in organic synthesis, particularly for introducing ketene functionalities into molecules for pharmaceutical and materials science applications.
What is the CAS number and formula for (Trimethylsilyl)ketene?
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The CAS number for (Trimethylsilyl)ketene is 4071-85-6, and its linear formula is (CH3)3SiCH=C=O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (Trimethylsilyl)ketene at a purity of 97%. This product is supplied for research and development purposes; TSS does not represent it as USP, BP, or EP grade.
How should (Trimethylsilyl)ketene be handled safely?
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(Trimethylsilyl)ketene is a highly flammable liquid and vapour (H225). Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a suitable respirator, in a well-ventilated area away from ignition sources. Consult the Safety Data Sheet for full handling information.
How is (Trimethylsilyl)ketene shipped and exported?
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As a flammable liquid (UN 1993, Class 3, PG II), (Trimethylsilyl)ketene is carefully packaged and shipped according to international regulations for hazardous materials. TSS is experienced in global export procedures.
How can I request a sample or quote for (Trimethylsilyl)ketene?
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To request a sample or obtain a quote for (Trimethylsilyl)ketene, please contact our sales department via the website or email, providing your specific requirements and shipping details.
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