4-Biphenylmagnesium bromide solution
4-Biphenylmagnesium bromide solution (CAS: 3315-91-1) is an organometallic compound with the linear formula C6H5C6H4MgBr and a molecular weight of 257.41 g/mol. Supplied as a 0.5 M solution in Tetrahydrofuran (THF), this aryl Grignard reagent is primarily utilised in chemical synthesis as a versatile building block for forming new carbon-carbon bonds, particularly in the development of complex organic molecules and pharmaceutical intermediates.
Carbon-Carbon Bond Formation
As a Grignard reagent, 4-Biphenylmagnesium bromide is instrumental in nucleophilic addition reactions, enabling the formation of carbon-carbon bonds with various electrophiles such as aldehydes, ketones, and esters. This reactivity is crucial in constructing complex molecular architectures.
Synthesis of Biaryl Compounds
This reagent serves as a key intermediate in the synthesis of substituted biphenyl derivatives, which are important structural motifs found in pharmaceuticals, agrochemicals, and advanced materials. Its use facilitates the introduction of the biphenyl moiety into target molecules.
Organometallic Chemistry
It is employed in diverse organometallic transformations, acting as a source of the 4-biphenyl group for coupling reactions and other synthetic methodologies within research and development settings.
| Molecular weight | 257.41 |
|---|---|
| Linear formula | C6H5C6H4MgBr |
| Boiling point | 65 °C |
| Density | 0.961 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Biphenylmagnesium bromide solution used for?
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4-Biphenylmagnesium bromide solution is used in organic synthesis for carbon-carbon bond formation and the preparation of biaryl compounds, serving as a versatile organometallic reagent.
What is the CAS number and formula for 4-Biphenylmagnesium bromide solution?
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The CAS number is 3315-91-1 and the linear formula is C6H5C6H4MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Biphenylmagnesium bromide solution at a concentration of 0.5 M in THF. As this is a technical or research grade material, TSS does not represent it as USP/BP/EP or any other pharmacopoeia grade.
How should 4-Biphenylmagnesium bromide solution be handled safely?
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This solution is flammable and corrosive, reacting violently with water and potentially forming explosive peroxides. Handle with extreme care in a well-ventilated area, wearing appropriate personal protective equipment including eyeshields, gloves, and a full-face respirator. Store at 2-8°C, away from ignition sources and incompatible materials.
How is 4-Biphenylmagnesium bromide solution shipped and exported?
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This product is classified under UN 2924 for transport, requiring specific packaging and handling procedures due to its hazardous nature. Tech Serve Solutions adheres to all international shipping and export regulations.
How can I request a sample or quote for 4-Biphenylmagnesium bromide solution?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (3315-91-1).
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