Stattic
Stattic (CAS: 19983-44-9, C8H5NO4S) is a bioactive small molecule used in cell biology research. This compound functions as an inhibitor, specifically targeting Stat3-mediated cell signalling pathways. With a molecular weight of 211.19 g/mol, Stattic is an important reagent for researchers investigating the role of STAT3 in various biological processes, particularly within oncology research. It is supplied by TSS with a minimum purity of 98%.
- IUPAC
- 6-Nitrobenzo[b]thiophene-1,1-dioxide,Stat three inhibitory compound
- Synonyms
- 6-Nitrobenzo[b]thiophene-1,1-dioxide,Stat three inhibitory compound
Investigating STAT3 Signalling
Stattic is utilised as a research tool to study the function of Signal Transducer and Activator of Transcription 3 (STAT3). It helps elucidate the downstream effects of STAT3 activation in cellular pathways.
Cancer Cell Biology Research
The compound has been employed in studies involving human lung carcinoma cells to understand STAT3-mediated cell signalling. This application aids in exploring potential therapeutic targets within cancer research.
Biochemical Pathway Analysis
As a STAT3 inhibitory compound, Stattic can be used to dissect the contributions of this specific signalling pathway in various biological contexts. Researchers use it to understand the consequences of inhibiting STAT3 activity.
| Molecular weight | 211.19 |
|---|---|
| Empirical formula | C8H5NO4S |
| Assay | ≥98% (HPLC) |
| Solubility | DMSO: >20 mg/mL |
| Application | Stattic was used to study Stat3-mediated cell signaling in human lung carcinoma cells.5 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Stattic used for?
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Stattic is used in research to study STAT3-mediated cell signalling, particularly in human lung carcinoma cells. It acts as an inhibitor for the STAT3 pathway.
What are the CAS number and formula for Stattic?
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The CAS number for Stattic is 19983-44-9, and its empirical formula is C8H5NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Stattic with a minimum purity of ≥98% as determined by HPLC. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should Stattic be handled safely?
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Stattic is classified with GHS07 and a 'Warning' signal word. It has hazard statements H302, H315, H319, and H335, indicating it is harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation. Recommended personal protective equipment includes a dust mask type N95, eyeshields, and gloves. Handle in a well-ventilated area.
Is Stattic a controlled substance?
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The provided data does not indicate that Stattic is a controlled substance.
How is Stattic packed and shipped?
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Stattic is available for export globally by Tech Serve Solutions. Packaging details are available upon request.
How can I request a sample or quote for Stattic?
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To request a sample or a quote for Stattic, please contact the TSS sales department through our website or by phone.
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