Spermine

CAS 71-44-3NH2(CH2)3NH(CH2)4NH(CH2)3NH2Biochemicals & Reagents

Spermine (CAS 71-44-3), with the molecular formula NH2(CH2)3NH(CH2)4NH(CH2)3NH2 and a molecular weight of 202.34 g/mol, is a polyamine found naturally in all eukaryotic cells. Supplied by Tech Serve Solutions as an amorphous semi-solid with an assay of ≥97%, it is primarily used in biochemical research and cell biology studies.

IUPAC: N,N′-Bis(3-aminopropyl)-1,4-diaminobutane,Gerontine,Musculamine,Neuridine
Synonyms: N,N′-Bis(3-aminopropyl)-1,4-diaminobutaneGerontineMusculamineNeuridine

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Spermine (NH2(CH2)3NH(CH2)4NH(CH2)3NH2) — chemical structure, CAS 71-44-3; Life Science, fine chemical supplied by Tech Serve Solutions

Application IndexBioactive Small MoleculesBiochemicals and ReagentsCell BiologyCell Signaling EnzymesEnzymesInhibitorsand SubstratesNOS InhibitorsNitric Oxide Metabolism

01 /Applications

Cell Biology Research

Spermine plays crucial roles in cell growth, differentiation, and survival. It is extensively used in laboratory settings to investigate cellular processes, nucleic acid interactions, and protein folding.

Biochemical Studies

As a naturally occurring polyamine, spermine is employed in biochemical assays to understand its interactions with DNA, RNA, and various proteins. It serves as a tool for studying enzyme regulation and metabolic pathways.

Cell Signaling Investigations

This compound is involved in various cell signaling cascades. Researchers utilise spermine to explore its influence on pathways related to cell stress, neurotransmission, and gene expression.

02 /Properties

Molecular weight	202.34
Linear formula	NH2(CH2)3NH(CH2)4NH(CH2)3NH2
Assay	≥97%
Form	amorphous semi-solid
Boiling point	150 °C/5 mmHg(lit.)
Storage temperature	2-8°C
Impurities tested	≤0.5% spermidine
Melting point	28-30(lit.)

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Flash point	110 °C / 230 °F
Transport (UN / ADR)	UN 3259PSN2 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34
Safety statements (S)	26-36/37/39-45
Anion traces	carbonate (CO32-): ≤5000 mg/kg

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

71-44-3

MDL number

MFCD00008215

PubChem substance

24899594

Beilstein registry

1750791

05 /Additional specifications

Product Line	BioReagent
Gene Information	human ... GRIN2B(2904)rat ... Grin2a(24409)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Spermine used for?

Spermine is primarily used in cell biology research and biochemical studies to investigate cellular processes, nucleic acid interactions, cell signaling, and its role in cell growth and differentiation.

What is the CAS number and formula for Spermine?

The CAS number for Spermine is 71-44-3, and its linear formula is NH2(CH2)3NH(CH2)4NH(CH2)3NH2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Spermine with an assay of ≥97% and an impurity level of ≤0.5% spermidine. This product is supplied as an amorphous semi-solid. Tech Serve Solutions does not represent this product as USP, BP, EP, or other pharmacopoeial grades.

How should Spermine be handled safely?

Spermine is classified as corrosive (H314), causing severe skin burns and eye damage. Handle with appropriate personal protective equipment, including safety goggles, face shields, and chemical-resistant gloves. Ensure adequate ventilation and use a respirator if exposure limits are exceeded. Refer to the Safety Data Sheet for detailed handling procedures.

How is Spermine packed, shipped, and exported?

Spermine is stored at 2-8°C. It is shipped under conditions appropriate for hazardous materials, indicated by UN 3259, PSN2, Class 8, Packing Group II. TSS is an experienced global exporter of fine chemicals.